The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …

Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose
tissue dysfunction and contributing to obesity-induced inflammation and metabolic …

In obesity, chronic low-grade inflammation is thought to mediate the effects of increased
adipose tissue mass on metabolic comorbidity. Of the different cell types that contribute to …

Obesity has become a worldwide epidemic that poses a severe threat to human health.
Evidence suggests that many obesity comorbidities, such as type 2 diabetes mellitus …

Obesity is characterized as a chronic state of low‐grade inflammation with progressive
immune cell infiltration into adipose tissues. Adipose tissue macrophages play critical roles …

Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …

It has long been known that adipose tissue in obesity is in a heightened state of
inflammation. Recently, our understanding of this has been transformed by the knowledge …

The expansion of adipose tissue (AT) in obesity is accompanied by the accumulation of
immune cells that contribute to a state of low‐grade, chronic inflammation and dysregulated …

The increasing prevalence of obesity is accompanied by a rising incidence in metabolic
syndrome and related pathologies such as non-alcoholic fatty liver disease. Macrophages …

Chronic, low-grade adipose tissue inflammation is a key etiological mechanism linking the
increasing incidence of type 2 diabetes (T2D) and obesity. It is well recognized that the …