The biological bases of nicotine and alcohol co-addiction

TK Li, ND Volkow, RD Baler… - Biological …, 2007 - biologicalpsychiatryjournal.com
Alcohol and nicotine kill over half a million Americans every year. Abuse and addiction to
these drugs represent the leading cause of preventable morbidity and mortality in the United …

Molecular, neuronal, and behavioral effects of ethanol and nicotine interactions

PM Klenowski, AR Tapper - The Neuropharmacology of Alcohol, 2018 - Springer
Ethanol and nicotine can modulate the activity of several neurotransmitter systems and
signalling pathways. Interactions between ethanol and nicotine can also occur via common …

Alcohol and nicotine interactions: pre-clinical models of dependence

JR Tarren, SE Bartlett - The American journal of drug and alcohol …, 2017 - Taylor & Francis
While the co-morbidity of alcohol (ethanol) and tobacco (nicotine) dependence is well
described, the processes that underpin this strong connection are still under debate. With …

[HTML][HTML] Biological processes underlying co-use of alcohol and nicotine: neuronal mechanisms, crosstolerance, and genetic factors

D Funk, PW Marinelli, AD Le - Alcohol Research & Health, 2006 - ncbi.nlm.nih.gov
Alcohol and nicotine are two of the oldest and most commonly used recreational drugs, and
many people use both of them together. Although their ready availability likely contributes to …

Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system

WM Doyon, AM Thomas, A Ostroumov, Y Dong… - Biochemical …, 2013 - Elsevier
Epidemiological studies consistently find correlations between nicotine and alcohol use, yet
the neural mechanisms underlying their interaction remain largely unknown. Nicotine and …

Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking

RM Leao, FC Cruz, LF Vendruscolo… - Journal of …, 2015 - Soc Neuroscience
Alcohol and nicotine are the two most co-abused drugs in the world. Previous studies have
shown that nicotine can increase alcohol drinking in nondependent rats, yet it is unknown …

Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence

LM Hendrickson, MJ Guildford, AR Tapper - Frontiers in psychiatry, 2013 - frontiersin.org
Alcohol and nicotine are often co-abused. As many as 80–95% of alcoholics are also
smokers, suggesting that ethanol and nicotine, the primary addictive component of tobacco …

The genetic components of alcohol and nicotine co-addiction: from genes to behavior

IR Schlaepfer, NR Hoft… - Current drug abuse …, 2008 - ingentaconnect.com
Co-occurrence of alcohol and nicotine addiction in humans is well documented and there is
good evidence that common genes may contribute to both disorders. Although genetic …

Comorbid alcohol and nicotine dependence: from the biomolecular basis to clinical consequences

N Ait‐Daoud, GA Wiesbeck… - Alcoholism: Clinical …, 2005 - Wiley Online Library
This article represents the proceedings of a symposium presented at the 12th Congress of
the International Society for Biomedical Research on Alcoholism held in …

Nicotine addiction and comorbidity with alcohol abuse and mental illness

JA Dani, RA Harris - Nature neuroscience, 2005 - nature.com
Abstract The World Health Organization estimates that one-third of the global adult
population smokes. Because tobacco use is on the rise in developing countries, death …