Transcriptome changes in dorsal spinal cord of rats with neuropathic pain
S Cao, J Yuan, D Zhang, S Wen, J Wang… - Journal of pain …, 2019 - Taylor & Francis
Background Mechanisms of neuropathic pain are not fully understood. Molecular changes in
spinal dorsal horn take part in the initiation and development of neuropathic pain. Methods …
spinal dorsal horn take part in the initiation and development of neuropathic pain. Methods …
Identification of IncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain
BC Jiang, WX Sun, LN He, DL Cao, ZJ Zhang… - Molecular …, 2015 - journals.sagepub.com
Background Neuropathic pain that caused by lesion or dysfunction of the nervous system is
associated with gene expression changes in the sensory pathway. Long noncoding RNAs …
associated with gene expression changes in the sensory pathway. Long noncoding RNAs …
Analyses of long non-coding RNA and mRNA profiles in the spinal cord of rats using RNA sequencing during the progression of neuropathic pain in an SNI model
J Zhou, Y Fan, H Chen - RNA biology, 2017 - Taylor & Francis
The pathogenesis of neuropathic pain (NP) is characterized by an increased
responsiveness of nociceptive neurons in the nervous system. However, the molecular …
responsiveness of nociceptive neurons in the nervous system. However, the molecular …
Analyses of gene expression profiles in the rat dorsal horn of the spinal cord using RNA sequencing in chronic constriction injury rats
H Du, J Shi, M Wang, S An, X Guo, Z Wang - Journal of neuroinflammation, 2018 - Springer
Background Neuropathic pain is caused by damage to the nervous system, resulting in
aberrant pain, which is associated with gene expression changes in the sensory pathway …
aberrant pain, which is associated with gene expression changes in the sensory pathway …
Gene transcript alterations in the spinal cord, anterior cingulate cortex, and amygdala in mice following peripheral nerve injury
S Su, M Li, D Wu, J Cao, X Ren, YX Tao… - Frontiers in Cell and …, 2021 - frontiersin.org
Chronic neuropathic pain caused by nerve damage is a most common clinical symptom,
often accompanied by anxiety-and depression-like symptoms. Current treatments are very …
often accompanied by anxiety-and depression-like symptoms. Current treatments are very …
Identification of Slc6a19os and SOX11 as two novel essential genes in neuropathic pain using integrated bioinformatic analysis and experimental verification
P Chen, C Wang, D Lin, B Li, S Ye, J Qu… - Frontiers in …, 2021 - frontiersin.org
The aim of this study was to identify critical genes associated with neuropathic pain. We also
used the competing endogenous RNA (ceRNA) hypothesis to identify related long non …
used the competing endogenous RNA (ceRNA) hypothesis to identify related long non …
Screening of disease-related biomarkers related to neuropathic pain (NP) after spinal cord injury (SCI)
J Zhao, L Yang, L Huang, Z Li - Human Genomics, 2021 - Springer
Background Based on the molecular expression level, this paper compares lncRNA and
mRNA expressions respectively in peripheral blood samples of the patients after SCI with …
mRNA expressions respectively in peripheral blood samples of the patients after SCI with …
Dorsal root ganglion transcriptome analysis following peripheral nerve injury in mice
S Wu, B Marie Lutz, X Miao, L Liang, K Mo… - Molecular …, 2016 - journals.sagepub.com
Background Peripheral nerve injury leads to changes in gene expression in primary sensory
neurons of the injured dorsal root ganglia. These changes are believed to be involved in …
neurons of the injured dorsal root ganglia. These changes are believed to be involved in …
Systematic analysis of critical genes and pathways identified a signature of neuropathic pain after spinal cord injury
Z Li, H Bai, R Zhang, B Chen, J Wang… - European Journal of …, 2022 - Wiley Online Library
Spinal cord injury (SCI) damages sensory systems, producing chronic neuropathic pain that
is resistant to medical treatment. The specific mechanisms underlying SCI‐induced …
is resistant to medical treatment. The specific mechanisms underlying SCI‐induced …
Genome-wide expression profiling by RNA-sequencing in spinal cord dorsal horn of a rat chronic postsurgical pain model to explore potential mechanisms involved in …
R Xu, J Wang, H Nie, D Zeng, C Yin, Y Li… - Journal of Pain …, 2022 - Taylor & Francis
Background Chronic postsurgical pain (CPSP) is common among patients receiving major
surgeries. CPSP produces suffering in patients, both physically and mentally. However, the …
surgeries. CPSP produces suffering in patients, both physically and mentally. However, the …
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