The pathogenesis of Chlamydia-induced inflammation is poorly understood. pORF5 is the
only secreted protein encoded by Chlamydial plasmid. This study aims to investigate the …

Infection with Chlamydia trachomatis induces inflammatory pathologies in the urogenital
tract that can lead to infertility and ectopic pregnancy. Pathogenesis of infection has been …

Purpose. Previous research demonstrated that IL-10 was up-regulated in Chlamydia
trachomatis-infected cells and that exogenous IL-10 was able to inhibit the secretion of pro …

Long non-coding RNAs (lncRNAs) have been demonstrated to play essential roles in many
diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of …

Chlamydia trachomatis infections represent the leading cause of bacterial sexually-
transmitted disease in the United States and can cause serious tissue damage leading to …

Chlamydia trachomatis is an important human pathogen responsible for a variety of
important diseases. pORF5, a plasmid protein in C. trachomatis, has been reported to …

The polymorphic membrane protein D (Pmp18D) is a 160-kDa outer membrane protein that
is conserved and plays an important role in Chlamydia abortus pathogenesis. We have …

Objective To determine the signaling pathway required for Chlamydial induction of IL-8
expression in epithelial cells. Methods The production and localization of IL-8 in Chlamydia …

Chlamydia trachomatis infects macrophages and epithelial cells evoking acute and chronic
inflammatory conditions, which, if not controlled, may put patients at risk for major health …

Aim Chlamydia trachomatis has evolved various strategies to alleviate oxidative stress of
host cells to maintain their intracellular survival. However, the exact mechanism of anti …