Caspase-1 Contributes to Chlamydia trachomatis-Induced Upper Urogenital Tract Inflammatory Pathologies without Affecting the Course of Infection

W Cheng, P Shivshankar, Z Li, L Chen… - Infection and …, 2008 - Am Soc Microbiol
Chlamydia trachomatis infection induces inflammatory pathologies in the upper genital tract,
potentially leading to ectopic pregnancy and infertility in the affected women. Caspase-1 is …

[HTML][HTML] Chlamydial plasmid-encoded virulence factor Pgp3 interacts with human cathelicidin peptide LL-37 to modulate immune response

S Hou, X Sun, X Dong, H Lin, L Tang, M Xue… - Microbes and …, 2019 - Elsevier
We have previously reported that Chlamydia trachomatis plasmid-encoded Pgp3 is able to
neutralize anti-chlamydial activity of human cathelicidin peptide LL-37 by binding to and …

Intracellular Interleukin-1α Mediates Interleukin-8 Production Induced by Chlamydia trachomatis Infection via a Mechanism Independent of Type I Interleukin-1 …

W Cheng, P Shivshankar, Y Zhong, D Chen… - Infection and …, 2008 - Am Soc Microbiol
Chlamydia trachomatis infection induces a wide array of inflammatory cytokines and
chemokines, which may contribute to chlamydia-induced pathologies. However, the precise …

Activation of the host cell proinflammatory interleukin‐8 response by Chlamydia trachomatis

KR Buchholz, RS Stephens - Cellular microbiology, 2006 - Wiley Online Library
Diseases associated with Chlamydia are caused by inflammation‐associated tissue
damage following repeated or chronic infection; however, the mechanism by which the …

MiR-184 targeting FOXO1 regulates host-cell oxidative stress induced by Chlamydia psittaci via the Wnt/β-catenin signaling pathway

L Chen, Q Huang, Y Luo, Y Zhou, T Tong… - Infection and …, 2023 - Am Soc Microbiol
Chlamydia psittaci is a human pathogen that causes atypical pneumonia after zoonotic
transmission. We confirmed that C. psittaci infection induces oxidative stress in human …

[HTML][HTML] Role of interleukin-4 (IL-4) in respiratory infection and allergy caused by early-life Chlamydia infection

S Li, L Wang, Y Zhang, L Ma, J Zhang… - Journal of microbiology …, 2021 - ncbi.nlm.nih.gov
Chlamydia pneumoniae is a type of pathogenic gram-negative bacteria that causes various
respiratory tract infections including asthma. Chlamydia species infect humans and cause …

Suppressors of cytokine signaling (SOCS) 1 and SOCS3 proteins are mediators of interleukin‐10 modulation of inflammatory responses induced by Chlamydia …

SA Duncan, R Sahu, S Dixit, SR Singh… - Mediators of …, 2020 - Wiley Online Library
The immunopathology of chlamydial diseases is exacerbated by a broad‐spectrum of
inflammatory mediators, which we reported are inhibited by IL‐10 in macrophages …

AP-1 transcription factor serves as a molecular switch between Chlamydia pneumoniae replication and persistence

S Krämer, P Crauwels, R Bohn, C Radzimski… - Infection and …, 2015 - Am Soc Microbiol
Chlamydia pneumoniae is a Gram-negative bacterium that causes acute or chronic
respiratory infections. As obligate intracellular pathogens, chlamydiae efficiently manipulate …

IL-10−/− Enhances DCs Immunity Against Chlamydia psittaci Infection via OX40L/NLRP3 and IDO/Treg Pathways

Q Li, X Li, H Quan, Y Wang, G Qu, Z Shen… - Frontiers in …, 2021 - frontiersin.org
Chlamydia psittaci (C. psittaci) is a common zoonotic agent that affects both poultry and
humans. Interleukin 10 (IL-10) is an anti-inflammatory factor produced during chlamydial …

Chlamydia trachomatis heat shock proteins 60 and 10 induce apoptosis in endocervical epithelial cells

R Jha, H Vardhan, S Bas, S Salhan, A Mittal - Inflammation Research, 2011 - Springer
Aim and objective The potential role of chlamydial heat shock proteins (cHSP) 60 and
cHSP10 in apoptosis of primary cervical epithelial cells was investigated. Methods Primary …