ABSTRACT Obstructive Sleep Apnea (OSA) is a common disorder that is associated with
disability, premature mortality and lost quality of life. Excessive daytime sleepiness and …

Obstructive sleep apnea is the most common sleep‐related breathing disorder worldwide
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …

Objective To review the effects of the circadian clock on homeostasis, the functional
interaction between the circadian clock and hypoxia-inducible factors, and the role of …

Obstructive sleep apnea (OSA) is a complex process that can lead to the dysregulation of
the molecular clock, as well as 24 h rhythms of sleep and wake, blood pressure, and other …

Identification and treatment of circadian rhythm sleep-wake disorders (CRSWDs) can be a
fascinating yet vexing clinical encounter in the Sleep Medicine realm. While circadian-based …

Abstract Background Obstructive Sleep Apnea (OSA) is a highly prevalent and
underdiagnosed sleep disorder. Recent studies suggest that OSA might disrupt the …

Abstract Study Objective: To test the hypothesis that respiratory event duration exhibits an
endogenous circadian rhythm. Design: Within-subject and between-subjects. Settings …

Sleep is an essential physiological process, which profoundly affects a wide range of
biological activities. It is now known that sleep supports myriad vital functions in the central …

Intermittent hypoxia (IH) is a major clinical feature of obstructive sleep apnea (OSA). The
mechanisms that become dysregulated after periods of exposure to IH are unclear …

Sleep-related respiratory dysfunction compromises the health and quality of life of millions of
people worldwide, underscoring the need for a full understanding of the mechanisms by …