Electrospun polyurethane-based vascular grafts: Physicochemical properties and functioning in vivo

AA Gostev, VS Chernonosova, IS Murashov… - Biomedical …, 2019 - iopscience.iop.org
General physicochemical properties of the vascular grafts (VGs) produced from the solutions
of Tecoflex (Tec) with gelatin (GL) and bivalirudin (BV) by electrospinning are studied. The …

In vivo stability of polyurethane-based electrospun vascular grafts in terms of chemistry and mechanics

AA Gostev, IK Shundrina, VI Pastukhov, AV Shutov… - Polymers, 2020 - mdpi.com
The biostability of the polyurethanes Tecoflex EG-80A and Pellethane 2363-80A, used as
basic polymers of the vascular grafts (VGs) produced by electrospinning, as well as the …

The preparation and performance of a new polyurethane vascular prosthesis

W He, Z Hu, A Xu, R Liu, H Yin, J Wang… - Cell biochemistry and …, 2013 - Springer
We investigated the performance of small-caliber polyurethane (PU) small-diameter
vascular prosthesis generated using the electrospinning technique. PU was electrospun into …

Development of biomimetic thermoplastic polyurethane/fibroin small‐diameter vascular grafts via a novel electrospinning approach

E Yu, HY Mi, J Zhang, JA Thomson… - Journal of Biomedical …, 2018 - Wiley Online Library
A new electrospinning approach for fabricating vascular grafts with a layered,
circumferentially aligned, and micro‐wavy fibrous structure similar to natural elastic tissues …

Development of an electrospun biomimetic polyurea scaffold suitable for vascular grafting

K Madhavan, MG Frid, K Hunter… - … Research Part B …, 2018 - Wiley Online Library
The optimization of biomechanical and biochemical properties of a vascular graft to render
properties relevant to physiological environments is a major challenge today. These critical …

Endothelial cell seeding of a 4-mm ID polyurethane vascular graft

C Fields, A Cassano, C Allen, A Meyer… - Journal of …, 2002 - journals.sagepub.com
We evaluated the extent (luminal coverage) of the endothelial cell (EC) lining/neointimal
development and the thromboresistance of electrostatically EC seeded small diameter …

Negative in vivo results despite promising in vitro data with a coated compliant electrospun polyurethane vascular graft

W Fortin, M Bouchet, E Therasse, M Maire… - Journal of Surgical …, 2022 - Elsevier
Introduction There is a growing need for small-diameter (< 6 mm) off-the-shelf synthetic
vascular conduits for different surgical bypass procedures, with actual synthetic conduits …

Fabrication and characterization of electrospun thermoplastic polyurethane/fibroin small-diameter vascular grafts for vascular tissue engineering

E Yu, J Zhang, JA Thomson, LS Turng - International Polymer …, 2016 - degruyter.com
The demand for small-diameter blood vessel substitutes has been increasing due to a
shortage of autograft vessels and problems with thrombosis and intimal hyperplasia with …

Modification, crosslinking and reactive electrospinning of a thermoplastic medical polyurethane for vascular graft applications

JP Theron, JH Knoetze, RD Sanderson, R Hunter… - Acta biomaterialia, 2010 - Elsevier
Thermoplastic polyurethanes are used in a variety of medical devices and experimental
tissue engineering scaffolds. Despite advances in polymer composition to improve their …

Electrospun small‐diameter polyurethane vascular grafts: ingrowth and differentiation of vascular‐specific host cells

H Bergmeister, C Grasl, I Walter, R Plasenzotti… - Artificial …, 2012 - Wiley Online Library
No small‐diameter synthetic graft has yet shown comparable performance to autologous
vessels. Synthetic conduits fail due to their inherent surface thrombogenicity and the …