Transcriptomic studies have demonstrated that the vast majority of the genomes of mammals
and other complex organisms is expressed in highly dynamic and cell-specific patterns to …

Mammalian genomes contain tens of thousands of long non-coding RNAs (lncRNAs) that
have been implicated in diverse biological processes. However, the lncRNA transcriptomes …

Mammals and other complex organisms can transcribe an abundance of long non-coding
RNAs (lncRNAs) that fulfill a wide variety of regulatory roles in many biological processes …

Long noncoding RNAs (lncRNAs) are pivotal regulators of genome structure and gene
expression. LncRNAs can directly interact with chromatin-modifying enzymes and …

Long non-coding RNAs (lncRNAs) are important transcripts that are more than 200
nucleotides in length, and distribute extensively in animal and plant genomes. Accumulated …

The functionality of long noncoding RNAs (lncRNAs) is disputed. In general, lncRNAs are
under weak selective pressures, suggesting that the majority of lncRNAs may be …

The human genome must be tightly packaged in order to fit inside the nucleus of a cell.
Genome organization is functional rather than random, which allows for the proper …

Over the past decade, thousands of long noncoding RNAs (lncRNAs) have been identified,
many of which play crucial roles in normal physiology and human disease. LncRNAs can …

Genomes of complex organisms encode an abundance and diversity of long noncoding
RNAs (lncRNAs) that are expressed throughout the cell and fulfill a wide variety of regulatory …

Long non-coding RNAs (lncRNAs) are increasingly being recognized as epigenetic
regulators of gene transcription. The diversity and complexity of lncRNA genes means that …