Evolutionary conservation of long non-coding RNAs; sequence, structure, function
P Johnsson, L Lipovich, D Grandér… - Biochimica et Biophysica …, 2014 - Elsevier
Background Recent advances in genomewide studies have revealed the abundance of long
non-coding RNAs (lncRNAs) in mammalian transcriptomes. The ENCODE Consortium has …
non-coding RNAs (lncRNAs) in mammalian transcriptomes. The ENCODE Consortium has …
Gathering around Firre
S Nakagawa, T Hirano - Nature Structural & Molecular Biology, 2014 - nature.com
Long noncoding RNAs (lncRNAs) have divergent roles in the nuclei of higher eukaryotes,
including chromatin modification and regulation of nuclear bodies. A new study adds a new …
including chromatin modification and regulation of nuclear bodies. A new study adds a new …
RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts
The increased application of transcriptome-wide profiling approaches has led to an
explosion in the number of documented long non-coding RNAs (lncRNAs). While these new …
explosion in the number of documented long non-coding RNAs (lncRNAs). While these new …
Volatile evolution of long noncoding RNA repertoires: mechanisms and biological implications
A Kapusta, C Feschotte - Trends in Genetics, 2014 - cell.com
Thousands of genes encoding long noncoding RNAs (lncRNAs) have been identified in all
vertebrate genomes thus far examined. The list of lncRNAs partaking in arguably important …
vertebrate genomes thus far examined. The list of lncRNAs partaking in arguably important …
Genome-wide analysis of RNA-chromatin interactions in lizards as a mean for functional lncRNA identification
M Tenorio, J Serwatowska, SL Fernandez-Valverde… - BMC genomics, 2023 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are defined as transcribed
molecules longer than 200 nucleotides with little to no protein-coding potential. LncRNAs …
molecules longer than 200 nucleotides with little to no protein-coding potential. LncRNAs …
The functions of long noncoding RNAs in development and stem cells
RBT Perry, I Ulitsky - Development, 2016 - journals.biologists.com
Eukaryotic genomes are pervasively transcribed, with tens of thousands of RNAs emanating
from uni-and bi-directional promoters and from active enhancers. In vertebrates, thousands …
from uni-and bi-directional promoters and from active enhancers. In vertebrates, thousands …
Intergenic lncRNAs and the evolution of gene expression
AC Marques, CP Ponting - Current opinion in genetics & development, 2014 - Elsevier
Eukaryote genomes encode a surprisingly large number of noncoding transcripts. Around
two-thirds of human transcribed loci do not encode protein, and many are intergenic and …
two-thirds of human transcribed loci do not encode protein, and many are intergenic and …
[HTML][HTML] Nuclear lncRNAs as epigenetic regulators—beyond skepticism
S Nakagawa, Y Kageyama - Biochimica et Biophysica Acta (BBA)-Gene …, 2014 - Elsevier
Systematic transcriptome analysis has revealed that a vast majority of the mammalian
genome is transcribed into RNA, thus establishing the concept of “pervasive transcription.” …
genome is transcribed into RNA, thus establishing the concept of “pervasive transcription.” …
Genome regulation by long noncoding RNAs
The central dogma of gene expression is that DNA is transcribed into messenger RNAs,
which in turn serve as the template for protein synthesis. The discovery of extensive …
which in turn serve as the template for protein synthesis. The discovery of extensive …
Non-coding RNA expression, function, and variation during Drosophila embryogenesis
Long non-coding RNAs (lncRNAs) can often function in the regulation of gene expression
during development; however, their generality as essential regulators in developmental …
during development; however, their generality as essential regulators in developmental …