[HTML][HTML] Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs
AC Marques, J Hughes, B Graham, MS Kowalczyk… - Genome biology, 2013 - Springer
Background Mammalian transcriptomes contain thousands of long noncoding RNAs
(lncRNAs). Some lncRNAs originate from intragenic enhancers which, when active, behave …
(lncRNAs). Some lncRNAs originate from intragenic enhancers which, when active, behave …
[HTML][HTML] Systematic analysis of genomic organization and structure of long non-coding RNAs in the human genome
The genomic architecture of several functional elements in animals and plants, such as
microRNAs and tRNA, has been better characterized. As yet, there is very little known about …
microRNAs and tRNA, has been better characterized. As yet, there is very little known about …
[HTML][HTML] Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs
Advances in vertebrate genomics have uncovered thousands of loci encoding long
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory …
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory …
Unique features of long non-coding RNA biogenesis and function
Long non-coding RNAs (lncRNAs) are a diverse class of RNAs that engage in numerous
biological processes across every branch of life. Although initially discovered as mRNA-like …
biological processes across every branch of life. Although initially discovered as mRNA-like …
The functions and unique features of long intergenic non-coding RNA
JD Ransohoff, Y Wei, PA Khavari - Nature reviews Molecular cell …, 2018 - nature.com
Long intergenic non-coding RNA (lincRNA) genes have diverse features that distinguish
them from mRNA-encoding genes and exercise functions such as remodelling chromatin …
them from mRNA-encoding genes and exercise functions such as remodelling chromatin …
[HTML][HTML] Extensive localization of long noncoding RNAs to the cytosol and mono-and polyribosomal complexes
S van Heesch, M van Iterson, J Jacobi, S Boymans… - Genome biology, 2014 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) form an abundant class of
transcripts, but the function of the majority of them remains elusive. While it has been shown …
transcripts, but the function of the majority of them remains elusive. While it has been shown …
Roles of long noncoding RNAs in chromosome domains
S Tomita, MOA Abdalla, S Fujiwara… - Wiley …, 2017 - Wiley Online Library
The cell nucleus is highly organized and functionally compartmentalized. Double‐stranded
naked DNA is complexed with core histones and assembled into nucleosomes and …
naked DNA is complexed with core histones and assembled into nucleosomes and …
[HTML][HTML] Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
[HTML][HTML] lincRNAs: genomics, evolution, and mechanisms
Long intervening noncoding RNAs (lincRNAs) are transcribed from thousands of loci in
mammalian genomes and might play widespread roles in gene regulation and other cellular …
mammalian genomes and might play widespread roles in gene regulation and other cellular …
Genome-wide analysis reveals distinct patterns of epigenetic features in long non-coding RNA loci
A major fraction of the transcriptome of higher organisms comprised an extensive repertoire
of long non-coding RNA (lncRNA) which express in a cell type and development stage …
of long non-coding RNA (lncRNA) which express in a cell type and development stage …