Macrophages can polarize into two different states (M1 and M2), which play contrasting
roles during pathogenesis or tissue damage. M1 polarized macrophages produce pro …

Macrophages, as crucial cellular components of innate immunity, are characterized by
possessing high plasticity and an abnormal ability to differentiate in response to numerous …

Macrophages, an important part of human immune system, possess a high plasticity and
heterogeneity (macrophage polarization) as classically activated macrophages (M1) and …

Macrophages are innate immune cells in the organism and can be found in almost tissues
and organs. They are highly plastic and heterogeneous cells and can participate in the …

Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

Macrophages as innate immune cells with great plasticity are of great interest for cell
therapy. There are two main macrophage populations–pro-and anti-inflammatory cells also …

Diversity and plasticity are two hallmarks of macrophages. M1 macrophages (classically
activated macrophages) are pro-inflammatory and have a central role in host defense …

Macrophage polarization has been well documented. Macrophages can aquire two
phenotypes, the pro-inflammatory M1 phenotype, and the anti-inflammatory and wound …

Monocytes/macrophages are heterogeneous and versatile cells that could undergo their
phenotypically/functionally dynamic switch in response to the microenvironment signals …

Objective In the present review, we try to critically evaluate the two faces of the macrophages
and their roles in relation to gene alteration in some inflammatory conditions. The pros-and …