The extent to which chromosomal gene position in prokaryotes affects local gene expression
remains an open question. Several studies have shown that chromosomal re-positioning of …

In bacteria, the contribution of global nucleoid organization in determining cellular
transcription programs is unclear. Using a mutant form of the most abundant nucleoid …

Some unidentified RNA molecules, together with the nucleoid protein HU, were suggested
to be involved in the nucleoid structure of Escherichia coli. HU is a conserved protein known …

The histone‐like protein HU is a highly abundant DNA architectural protein that is involved
in compacting the DNA of the bacterial nucleoid and in regulating the main DNA …

The nucleoid-associated protein HU is one of the most abundant proteins in Escherichia coli
and has been suggested to play an important role in bacterial nucleoid organization and …

H-NS is a protein of the bacterial nucleoid involved in DNA compaction and transcription
regulation. In vivo, H-NS selectively silences specific genes of the bacterial chromosome …

Cellular adaptation to changing environmental conditions requires the coordinated
regulation of expression of large sets of genes by global regulatory factors such as nucleoid …

Bacterial nucleoid organization is believed to have minimal influence on the global
transcription program. Using an altered bacterial histone-like protein, HUα, we show that …

We determined the crystal structure of the Escherichia coli nucleoid-associated HUαβ
protein by x-ray diffraction and observed that the heterodimers form multimers with octameric …

IHF and HU are two heterodimeric nucleoid-associated proteins (NAP) that belong to the
same protein family but interact differently with the DNA. IHF is a sequence-specific DNA …