Short-course chemotherapy is highly efficacious in treating tuberculosis (TB). However, the
length (≥ 6 months) and complexity (three or four different drugs) of the treatment makes …

Worldwide, tuberculosis (TB) remains one of the most important communicable diseases in
terms of morbidity and mortality. Its control requires multi‐drug therapy for at least six months …

There is considerable exigency to take all necessary steps to cure tuberculosis cases and
prevent further emergence of drug-resistant tuberculosis. The most important of these steps …

The World Health Organization (WHO) has promoted the DOTS strategy as the essential,
most cost-effective package for tuberculosis control since 1994. Today, the 148 countries …

EXECUTIVE SUMMARY The World Health Organization (WHO) has continually emphasized
that to confront the global tuberculosis emergency, all the elements of the framework of …

Study C was an open-label, non-inferiority, randomised controlled trial of fixed-dose
combination (FDC) or separate drugs given during the intensive phase of treatment to 1585 …

Fixed-dose combination (FDC) formulations are currently recommended for the treatment of
active tuberculosis (TB). We have conducted a systematic review to evaluate the risk of …

Background There are limited data on the performance of the use of fixed-dose combination
(FDC) TB drugs when used under programmatic settings in high TB-endemic countries. We …

Uptake of fixed-dosed combinations (FDCs) of anti-tuberculosis drugs remains low
worldwide, despite decades of recommendations. FDCs are thought to be important tools for …

Access to tuberculosis drugs depends on multiple factors. Selection of a standard list of TB
drugs to procure is the first step. This paper reviews the advantages and disadvantages of …