Bioinspired copper single‐atom nanozyme as a superoxide dismutase‐like antioxidant for sepsis treatment

J Yang, R Zhang, H Zhao, H Qi, J Li, JF Li, X Zhou… - …, 2022 - Wiley Online Library
Sepsis is a systemic inflammatory response syndrome with high morbidity and mortality
mediated by infection‐caused oxidative stress. Early antioxidant intervention by removing …

Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases

T Liu, B Xiao, F Xiang, J Tan, Z Chen, X Zhang… - Nature …, 2020 - nature.com
Oxidative stress is associated with many acute and chronic inflammatory diseases, yet
limited treatment is currently available clinically. The development of enzyme-mimicking …

Quaternized chitosan coated copper sulfide nanozyme with peroxidase-like activity for synergistic antibacteria and promoting infected wound healing

B Luo, J Cai, Y Xiong, X Ding, X Li, S Li, C Xu… - International Journal of …, 2023 - Elsevier
Bacterial infection can hinder the infected wound healing process. Because of the growing
drug-resistance bacteria, there is an urgent desire to develop alternative antibacterial …

Functional molecule-mediated assembled copper nanozymes for diabetic wound healing

W Huang, P Xu, X Fu, J Yang, W Jing, Y Cai… - Journal of …, 2023 - Springer
Background The complex hyperglycemic, hypoxic, and reactive oxygen species
microenvironment of diabetic wound leads to vascular defects and bacterial growth and …

Atomically Dispersed Cu Nanozyme with Intensive Ascorbate Peroxidase Mimic Activity Capable of Alleviating ROS‐Mediated Oxidation Damage

Y Chen, H Zou, B Yan, X Wu, W Cao, Y Qian… - Advanced …, 2022 - Wiley Online Library
Ascorbate peroxidase (APX) as a crucial antioxidant enzyme has drawn attentions for its
utilization in preventing cells from oxidative stress responses by efficiently scavenging H2O2 …

Engineering antioxidative cascade metal-phenolic nanozymes for alleviating oxidative stress during extracorporeal blood purification

Z Wei, G Peng, Y Zhao, S Chen, R Wang, H Mao… - ACS …, 2022 - ACS Publications
Oxidative stress is a compelling risk factor in chronic kidney diseases and is further
aggravated for individuals during extracorporeal blood purification, ultimately leading to …

Superoxide-like Cu/GO single-atom catalysts nanozyme with high specificity and activity for removing superoxide free radicals

M Lu, J Wang, G Ren, F Qin, Z Zhao, K Li, W Chen… - Nano Research, 2022 - Springer
Although nanozyme has become an emerging area of research attracting extensive
attention recently, the activity and specificity of currently reported nanozymes are generally …

Alternative copper-based single-atom nanozyme with superior multienzyme activities and nir-ii responsiveness to fight against deep tissue infections

J Bai, Y Feng, W Li, Z Cheng, JM Rosenholm, H Yang… - Research, 2023 - spj.science.org
Nanozymes are considered to represent a new era of antibacterial agents, while their
antibacterial efficiency is limited by the increasing tissue depth of infection. To address this …

CuO2-assisting-Zn single atom hybrid nanozymes for biofilm-infected wound healing

J Song, H Chen, Y Lv, W Yang, F Zhang, T Wang… - Chemical Engineering …, 2023 - Elsevier
Abstract Single-atom catalysts (SACs), characterized by atomically dispersed single metal
atoms, provide superior antibacterial properties over common nanozyme materials due to …

Efficient elimination of multidrug-resistant bacteria using copper sulfide nanozymes anchored to graphene oxide nanosheets

W Wang, B Li, H Yang, Z Lin, L Chen, Z Li, J Ge… - Nano Research, 2020 - Springer
Antibacterial nanomaterials have attracted growing interest for bacterial infection therapy.
However, most nanomaterials eliminate bacteria either physically or chemically, which …