Microsatellite Stable Colorectal Cancers Stratified by the BRAF V600E Mutation Show Distinct Patterns of Chromosomal Instability
The BRAF (V600E) mutation in colorectal cancers that are microsatellite stable (MSS)
confers a poor patient prognosis, whereas BRAF mutant microsatellite-unstable (MSI) …
confers a poor patient prognosis, whereas BRAF mutant microsatellite-unstable (MSI) …
Chromosomal Instability in BRAF Mutant, Microsatellite Stable Colorectal Cancers
The BRAF oncogene is mutated in 15% of sporadic colorectal cancers. Approximately half of
these BRAF mutant cancers demonstrate frequent frameshift mutations termed microsatellite …
these BRAF mutant cancers demonstrate frequent frameshift mutations termed microsatellite …
Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers
EMV De Cuba, P Snaebjornsson… - … journal of cancer, 2016 - Wiley Online Library
Microsatellite instability (MSI) has been associated with favourable survival in early stage
colorectal cancer (CRC) compared to microsatellite stable (MSS) CRC. The BRAF V600E …
colorectal cancer (CRC) compared to microsatellite stable (MSS) CRC. The BRAF V600E …
Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication
P Lochhead, A Kuchiba, Y Imamura… - Journal of the …, 2013 - academic.oup.com
BRAF mutation in colorectal cancer is associated with microsatellite instability (MSI) through
its relationship with high-level CpG island methylator phenotype (CIMP) and MLH1 promoter …
its relationship with high-level CpG island methylator phenotype (CIMP) and MLH1 promoter …
Prognostic value of the combination of microsatellite instability and BRAF mutation in colorectal cancer
Purpose The aim of this study was to investigate the prognostic value of the combination of
microsatellite instability (MSI) and BRAF V600E mutation in colorectal cancer (CRC) …
microsatellite instability (MSI) and BRAF V600E mutation in colorectal cancer (CRC) …
Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer
TT Seppälä, JP Böhm, M Friman, L Lahtinen… - British journal of …, 2015 - nature.com
Background: The objective of the study was to examine the role of microsatellite instability
(MSI) and BRAF V600E mutation in colorectal cancer (CRC) by categorising patients into …
(MSI) and BRAF V600E mutation in colorectal cancer (CRC) by categorising patients into …
The association between mutations in BRAF and colorectal cancer–specific survival depends on microsatellite status and tumor stage
H Bläker, E Alwers, A Arnold, E Herpel… - Clinical …, 2019 - Elsevier
Background & Aims Colorectal tumors with mutations in BRAF and microsatellite stability
(MSS) have been associated with adverse outcomes of patients. Combined tests for …
(MSS) have been associated with adverse outcomes of patients. Combined tests for …
Prognostic impact of BRAF V600E mutation in patients with non-metastatic colorectal cancer with microsatellite instability: A systematic review and meta-analysis.
S Manthravadi, W Sun, A Saeed - 2018 - ascopubs.org
3597 Background: Colorectal cancer (CRC) displaying high levels of microsatellite instability
(MSI-H) has been associated with improved survival in colorectal cancer. MSI-H CRC is also …
(MSI-H) has been associated with improved survival in colorectal cancer. MSI-H CRC is also …
MSI status is associated with distinct clinicopathological features in BRAF mutation colorectal cancer: A systematic review and meta-analysis
M Wu, YS Kim, HS Ryu, SC Choi, KY Kim… - … -Research and Practice, 2020 - Elsevier
Abstract Background Microsatellite stable (MSS) BRAF p. V600E mutation colorectal cancer
(BRAF-CRC) has a poor prognosis, whereas microsatellite instability (MSI) in BRAF-CRC is …
(BRAF-CRC) has a poor prognosis, whereas microsatellite instability (MSI) in BRAF-CRC is …
BRAF-mutated microsatellite stable colorectal carcinoma: an aggressive adenocarcinoma with reduced CDX2 and increased cytokeratin 7 immunohistochemical …
Reduced CDX2 and cytokeratin 20 (CK20) expression in colorectal carcinoma with BRAF
mutation and high-level microsatellite instability (MSI-H) has been well documented. The …
mutation and high-level microsatellite instability (MSI-H) has been well documented. The …
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