Rationale Modafinil is a first-line wake-promoting medication and a useful therapeutic
alternative to psychostimulant medications for excessive daytime sleepiness. Objective This …

Objectives: To assess the efficacy and safety of modafinil for improving wakefulness in
narcolepsy patients treated previously with psychostimulants. Background: Modafinil has …

Objectives: To assess the long-term efficacy and safety of modafinil in patients with
excessive daytime sleepiness (EDS) associated with narcolepsy. Background: Modafinil has …

In a multicenter, randomized, double-blind study the authors compared the efficacy of
modafinil 400 mg once daily, 400 mg given in a split dose, or 200 mg once daily for …

■ ABSTRACT Modafinil (Provigil) is approved for treating excessive daytime sleepiness
associated with narcolepsy, for shiftwork sleep disorder, and as an adjunctive treatment in …

Objectives: A modafinil daily dosing strategy promotes wakefulness in narcolepsy patients
experiencing excessive daytime sleepiness; however, some patients may continue to …

Study objectives Modafinil is a common treatment for excessive daytime sleepiness (EDS) in
narcolepsy. The long-term use of modafinil can lead to tolerance with the loss of efficacy and …

Study Objectives: Modafinil is a wake-promoting agent shown to improve wakefulness in
patients with excessive sleepiness (hypersomnolence) associated with shift work sleep …

Background Few treatments are available for patients with idiopathic hypersomnia (IH).
Modafinil, an established treatment for narcolepsy, was tested for efficacy and safety in …

Objective: To assess the continued efficacy of modafinil in the treatment of excessive
daytime somnolence (EDS) of narcolepsy. Background: Modafinil has been shown to be a …