The anti-IL-4 receptor alpha antibody dupilumab: facing a new era in treating atopic dermatitis

A Tsianakas, TA Luger - Expert Opinion on Biological Therapy, 2015 - Taylor & Francis
Introduction: Atopic dermatitis is the most common chronic inflammatory skin disease with
high prevalence rates in adults and even higher among children. For the numerous patients …

Dupilumab in atopic dermatitis

M Lázaro-Sastre, A García-Sánchez… - … Treatment Options in …, 2019 - Springer
Purpose of review Atopic dermatitis (AD) is a common chronic inflammatory relapsing skin
disease that greatly affects the quality of life of patients and their relatives. Topical treatment …

Dupilumab in atopic dermatitis: rationale, latest evidence and place in therapy

LFM Ariëns, DS Bakker… - … advances in chronic …, 2018 - journals.sagepub.com
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. The
prevalence of AD is increasing and is currently estimated at 10–20% in adults worldwide. In …

Real‐world experience of dupilumab treatment for atopic dermatitis in adults: a retrospective analysis of patients' records

C Wang, CN Kraus, KG Patel… - International Journal …, 2020 - Wiley Online Library
Background Clinical trial data for dupilumab, a monoclonal antibody against the interleukin‐
4 receptor (IL‐4Rα), have shown that it is safe and effective for the treatment of moderate to …

[HTML][HTML] Dupilumab for the treatment of atopic dermatitis

S Ferreira, T Torres - Actas Dermo-Sifiliográficas (English Edition), 2018 - Elsevier
Atopic dermatitis (AD) is a common, chronic, inflammatory skin disorder with high physical
and emotional burden. AD usually starts in early childhood and has a heterogeneous …

Dupilumab use in atopic dermatitis and beyond in skin diseases

K Fourzali, RS Golpanian, G Yosipovitch - Immunotherapy, 2020 - Taylor & Francis
Atopic dermatitis (AD) is a chronic inflammatory condition that affects 5–10% of adults and 9–
18% of children and its pathology is rooted in the Th-2-mediated immune response …

Profile of dupilumab and its potential in the treatment of inadequately controlled moderate-to-severe atopic dermatitis

O Awosika, L Kim, M Mazhar… - Clinical, cosmetic and …, 2018 - Taylor & Francis
Atopic dermatitis (AD) is a common inflammatory skin disorder that manifests as eczematous
lesions, often associated with allergic rhinitis and asthma. Historically, moderate-to-severe …

Dupilumab for the treatment of atopic dermatitis: a clinical trial review

S McGregor, ME Farhangian… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Current treatment options for moderate-to-severe atopic dermatitis (AD) are
limited and have potentially dangerous side effects. Dupilumab is a novel monoclonal …

Dupilumab: an evidence-based review of its potential in the treatment of atopic dermatitis

P Eshtiaghi, MJ Gooderham - Core evidence, 2018 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a recurrent, pruritic inflammatory skin disease with
complex immunopathogenesis characterized by a dominant TH2 response. Dupilumab is an …

Dupilumab in the treatment of moderate-to-severe atopic dermatitis

M Kraft, M Worm - Expert review of clinical immunology, 2017 - Taylor & Francis
Introduction: Atopic dermatitis is a common inflammatory skin disease with an increasing
prevalence. Treatment of patients suffering from mild or moderate disease includes the use …