HIV neurotoxicity: potential therapeutic interventions

DR Wallace - BioMed Research International, 2006 - Wiley Online Library
Individuals suffering from human immunodeficiency virus type 1 (HIV‐1) infection suffer from
a wide range of neurological deficits. The most pronounced are the motor and cognitive …

HIV-associated neurotoxicity and cognitive decline: Therapeutic implications

DR Wallace - Pharmacology & Therapeutics, 2022 - Elsevier
As our understanding of changes to the neurological system has improved, it has become
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …

Neuropathogenesis of AIDS

S Dewhurst, HA Gelbard, SM Fine - Molecular Medicine Today, 1996 - Elsevier
Neurological disease directly attributable to HIV-1 infection (HIV dementia) is one of the
most frequent disorders in persons with AIDS. HIV-1 dementia is associated with neuronal …

HIV‐Associated Neurotoxicity: The Interplay of Host and Viral Proteins

S Jadhav, V Nema - Mediators of Inflammation, 2021 - Wiley Online Library
HIV‐1 can incite activation of chemokine receptors, inflammatory mediators, and glutamate
receptor‐mediated excitotoxicity. The mechanisms associated with such immune activation …

CNS neurotoxicity of antiretrovirals

T Lanman, S Letendre, Q Ma, A Bang… - Journal of Neuroimmune …, 2021 - Springer
The development of novel antiretroviral treatments has led to a significant turning point in the
fight against HIV. Although therapy leads to virologic suppression and prolonged life …

HIV-1 infection and AIDS: consequences for the central nervous system

M Kaul, J Zheng, S Okamoto, HE Gendelman… - Cell Death & …, 2005 - nature.com
Infection with the human immunodeficiency virus-1 (HIV-1) can induce severe and
debilitating neurological problems that include behavioral abnormalities, motor dysfunction …

Mechanisms of neuronal injury and death in HIV-1 associated dementia

M Kaul, SA Lipton - Current HIV research, 2006 - ingentaconnect.com
Infection with the human immunodeficiency virus-1 (HIV-1) and acquired immunodeficiency
syndrome (AIDS) remain a persistent and even growing health problem worldwide. Besides …

Neurobiology of HIV

B Hult, G Chana, E Masliah, I Everall - International Review of …, 2008 - Taylor & Francis
The importance of HIV cognitive impairment, including HIV associated dementia (HAD) and
minor cognitive/motor disorder, has continued in the era of highly active antiretroviral …

[HTML][HTML] HIV's double strike at the brain: neuronal toxicity and compromised neurogenesis

M Kaul - Frontiers in bioscience: a journal and virtual library, 2008 - ncbi.nlm.nih.gov
Infection with the human immunodeficiency virus-1 (HIV-1) and acquired immunodeficiency
syndrome (AIDS) are often associated with severe and debilitating neurological problems …

Pathogenesis of HIV-1 associated neurodegeneration

E Masliah, N Ge, L Mucke - Critical Reviews™ in Neurobiology, 1996 - dl.begellhouse.com
ABSTRACT A significant number of people infected with the human immunodeficiency virus
(HIV) develop neurologic complications. The AIDS dementia complex is frequently …