The mammalian lens consists of an aged core of quiescent cells enveloped by a layer of
synthetically active cells. Abundant gap junctions within and between these cell populations …

The lens is an avascular organ that transmits and focuses light images onto the retina.
Intercellular gap junction channels, formed by at least three different connexin protein …

Both connexins and signal transduction pathways have been independently shown to play
critical roles in lens homeostasis, but little is known about potential cooperation between …

The cells of most mammalian organs are connected by groups of cell-to-cell channels called
gap junctions. Gap junction channels are made from the connexin (Cx) family of proteins …

Gap junctions are composed of proteins called connexins (Cx) and facilitate both ionic and
biochemical modes of intercellular communication. In the lens, Cx46 and Cx50 provide the …

purpose. To determine the role of PKCγ in insulin-like growth factor (IGF)-I-induced
phosphorylation of connexin (Cx) 43 and control of gap junctions in lens epithelial cells …

Epithelial cells in primary ovine lens cultures express the gap junction proteins connexin43
(Cx43) and connexin49 (Cx49; aka MP70), a homologue of mouse connexin50. In contrast …

Gap junctions in the epithelium and superficial fiber cells from young mice were examined in
lenses prepared by rapid-freezing, and processed for freeze-substitution and freeze-fracture …

purpose. To map changes in the structure and function of fiber cell gap junctions that occur
with lens differentiation. methods. Equatorial lens sections were fluorescently labeled with …

PURPOSE: Within the corneal stroma, keratocytes communicate through gap junctions.
These plasma membrane channels, which connect the cytoplasm of adjacent cells, are …