Particle characterization and toxicity in C57BL/6 mice following instillation of five different diesel exhaust particles designed to differ in physicochemical properties
Background Diesel exhaust is carcinogenic and exposure to diesel particles cause health
effects. We investigated the toxicity of diesel exhaust particles designed to have varying …
effects. We investigated the toxicity of diesel exhaust particles designed to have varying …
Sample characterization of automobile and forklift diesel exhaust particles and comparative pulmonary toxicity in mice.
P Singh, DM DeMarini, CAJ Dick… - Environmental …, 2004 - ehp.niehs.nih.gov
Two samples of diesel exhaust particles (DEPs) predominate in health effects research: an
automobile-derived DEP (A-DEP) sample and the National Institute of Standards …
automobile-derived DEP (A-DEP) sample and the National Institute of Standards …
Composition of diesel particles influences acute pulmonary toxicity: an experimental study in mice
D Laks, R de Oliveira, P de André… - Inhalation …, 2008 - Taylor & Francis
Ambient particles have been consistently associated with adverse health effects, yielding
mainly high cardiorespiratory morbidity and mortality. Diesel engines represent a major …
mainly high cardiorespiratory morbidity and mortality. Diesel engines represent a major …
Chemical characterization and in vitro toxicity of diesel exhaust particulate matter generated under varying conditions
JR Fox, DP Cox, BE Drury, TR Gould… - Air Quality, Atmosphere …, 2015 - Springer
Epidemiologic studies have linked diesel exhaust (DE) to cardiovascular and respiratory
morbidity and mortality, as well as lung cancer. DE composition is known to vary with many …
morbidity and mortality, as well as lung cancer. DE composition is known to vary with many …
Effects of fuel components and combustion particle physicochemical properties on toxicological responses of lung cells
IC Jaramillo, A Sturrock, H Ghiassi… - … Science and Health …, 2018 - Taylor & Francis
The physicochemical properties of combustion particles that promote lung toxicity are not
fully understood, hindered by the fact that combustion particles vary based on the fuel and …
fully understood, hindered by the fact that combustion particles vary based on the fuel and …
Route of exposure alters inflammation and lung function responses to diesel exhaust
Context: Mice are commonly used in studies investigating the effects of diesel exhaust
exposure on respiratory health. A plethora of studies in this field has resulted in a range of …
exposure on respiratory health. A plethora of studies in this field has resulted in a range of …
Cellular response to diesel exhaust particles strongly depends on the exposure method
AL Holder, D Lucas, R Goth-Goldstein… - Toxicological …, 2008 - academic.oup.com
In vitro exposure to aerosols at the air–liquid interface (ALI) preserves the physical and
chemical characteristics of aerosol particles. Although frequently described as being a more …
chemical characteristics of aerosol particles. Although frequently described as being a more …
DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice
ZO Kyjovska, NR Jacobsen, AT Saber… - …, 2015 - academic.oup.com
We investigated the inflammatory response, acute phase response and genotoxic effect of
diesel exhaust particles (DEPs, NIST1650b) following a single intratracheal instillation …
diesel exhaust particles (DEPs, NIST1650b) following a single intratracheal instillation …
In vitro pulmonary and vascular effects induced by different diesel exhaust particles
Diesel exhaust particles (DEP) are responsible for both respiratory and cardiovascular
effects. However many questions are still unravelled and the mechanisms behind the health …
effects. However many questions are still unravelled and the mechanisms behind the health …
Physiological and inflammatory responses in an anthropomorphically relevant model of acute diesel exhaust particle exposure are sex and dose-dependent
Context: Diesel exhaust particles (DEP) are an important contributor to suspended
particulate matter (PM) in urban areas. While epidemiological evidence exists for a sex …
particulate matter (PM) in urban areas. While epidemiological evidence exists for a sex …