Particle characterization and toxicity in C57BL/6 mice following instillation of five different diesel exhaust particles designed to differ in physicochemical properties

KM Bendtsen, L Gren, VB Malmborg, PC Shukla… - Particle and Fibre …, 2020 - Springer
Background Diesel exhaust is carcinogenic and exposure to diesel particles cause health
effects. We investigated the toxicity of diesel exhaust particles designed to have varying …

Sample characterization of automobile and forklift diesel exhaust particles and comparative pulmonary toxicity in mice.

P Singh, DM DeMarini, CAJ Dick… - Environmental …, 2004 - ehp.niehs.nih.gov
Two samples of diesel exhaust particles (DEPs) predominate in health effects research: an
automobile-derived DEP (A-DEP) sample and the National Institute of Standards …

Composition of diesel particles influences acute pulmonary toxicity: an experimental study in mice

D Laks, R de Oliveira, P de André… - Inhalation …, 2008 - Taylor & Francis
Ambient particles have been consistently associated with adverse health effects, yielding
mainly high cardiorespiratory morbidity and mortality. Diesel engines represent a major …

Chemical characterization and in vitro toxicity of diesel exhaust particulate matter generated under varying conditions

JR Fox, DP Cox, BE Drury, TR Gould… - Air Quality, Atmosphere …, 2015 - Springer
Epidemiologic studies have linked diesel exhaust (DE) to cardiovascular and respiratory
morbidity and mortality, as well as lung cancer. DE composition is known to vary with many …

Effects of fuel components and combustion particle physicochemical properties on toxicological responses of lung cells

IC Jaramillo, A Sturrock, H Ghiassi… - … Science and Health …, 2018 - Taylor & Francis
The physicochemical properties of combustion particles that promote lung toxicity are not
fully understood, hindered by the fact that combustion particles vary based on the fuel and …

Route of exposure alters inflammation and lung function responses to diesel exhaust

AN Larcombe, JA Phan, A Kicic, KL Perks… - Inhalation …, 2014 - Taylor & Francis
Context: Mice are commonly used in studies investigating the effects of diesel exhaust
exposure on respiratory health. A plethora of studies in this field has resulted in a range of …

Cellular response to diesel exhaust particles strongly depends on the exposure method

AL Holder, D Lucas, R Goth-Goldstein… - Toxicological …, 2008 - academic.oup.com
In vitro exposure to aerosols at the air–liquid interface (ALI) preserves the physical and
chemical characteristics of aerosol particles. Although frequently described as being a more …

DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice

ZO Kyjovska, NR Jacobsen, AT Saber… - …, 2015 - academic.oup.com
We investigated the inflammatory response, acute phase response and genotoxic effect of
diesel exhaust particles (DEPs, NIST1650b) following a single intratracheal instillation …

In vitro pulmonary and vascular effects induced by different diesel exhaust particles

R Bengalli, A Zerboni, S Marchetti, E Longhin, M Priola… - Toxicology letters, 2019 - Elsevier
Diesel exhaust particles (DEP) are responsible for both respiratory and cardiovascular
effects. However many questions are still unravelled and the mechanisms behind the health …

Physiological and inflammatory responses in an anthropomorphically relevant model of acute diesel exhaust particle exposure are sex and dose-dependent

CE Boylen, PD Sly, GR Zosky… - Inhalation toxicology, 2011 - Taylor & Francis
Context: Diesel exhaust particles (DEP) are an important contributor to suspended
particulate matter (PM) in urban areas. While epidemiological evidence exists for a sex …