The CRISPR/Cas9 revolution has democratized access to genome editing in many
biological fields, including cancer research. Cancer results from the multistep accumulation …

The cancer-modelling field is now experiencing a conversion with the recent emergence of
the RNA-programmable CRISPR-Cas9 system, a flexible methodology to produce …

In just a few short years, CRISPR/Cas9 genome editing has fundamentally changed basic,
agricultural, and biomedical research, but no field has felt a more profound impact than …

CRISPR/Cas9 systems have revolutionised the field of gene editing, allowing for precise
modifications to be generated in vivo to mimic the genetic events found in human cancer …

Since its introduction to genome editing, CRISPR-Cas9 has been used to generate cell and
animal models of disease, investigate relations between genomes and phenotypes, and …

CRISPR-Cas9 is an RNA-guided site-specific DNA editing tool which, together with its
reprogrammed versions such as nickase Cas9 and dead Cas9, enables quick modeling of …

CRISPR-Cas9 has quickly become the method of choice for genome editing, with multiple
publications describing technical advances and novel applications. It has been widely …

The cancer genome is highly complex, with hundreds of point mutations, translocations, and
chromosome gains and losses per tumor. To understand the effects of these alterations …

With the expansion of the microbiology field of research, a new genome editing tool arises
from the biology of bacteria that holds the promise of achieving precise modifications in the …

Cancer development is a multistep process triggered by innate and acquired mutations,
which cause the functional abnormality and determine the initiation and progression of …