Genetic mutations affecting human lipoproteins, their receptors, and their enzymes

VI Zannis, D Kardassis, EE Zanni - Advances in Human Genetics 21, 1993 - Springer
Lipoproteins are macromolecular complexes of lipids and proteins which originate mainly
from the liver and intestine, and are involved in the transport and redistribution of lipids in the …

Genetic mutations affecting human lipoprotein metabolism

VI Zannis, JL Breslow - Advances in Human Genetics 14, 1985 - Springer
Lipoproteins are macromolecular complexes of lipids and proteins that are synthesized
mainly by the liver and intestine and catabolized by hepatic and extrahepatic tissues. Their …

[PDF][PDF] Genetic basis of lipoprotein disorders.

JL Breslow - The Journal of clinical investigation, 1989 - Am Soc Clin Investig
Lipoproteins are complexes of lipids and proteins that carry cholesterol in the bloodstream.
They are spherical particles with a coat consisting principally of amphiphilic phospho-lipids …

[引用][C] Apolipoprotein function in health and disease: insights from natural mutations

G Franceschini - European journal of clinical investigation, 1996 - Wiley Online Library
Plasma lipoproteins are water-soluble macromolecules composed of lipids and one or more
specific proteins called apolipoproteins (apos). Human apolipoproteins have distinct …

Genetics of lipoprotein disorders.

JL Breslow - Circulation, 1993 - europepmc.org
Lipoproteins are circulating complexes of lipids and proteins, the transport and metabolism
of which are directly controlled by apolipoproteins AI, A-II, A-IV, B, CI, C-II, C-III, D, E, and (a); …

[引用][C] Human apolipoprotein molecular biology and genetic variation

JL Breslow - Annual review of biochemistry, 1985 - annualreviews.org
Apolipoproteins are important structural constituents of lipoprotein particles and have been
shown to participate in lipoprotein synthesis, secretion, proces sing, and catabolism. These …

[HTML][HTML] Genetic factors affecting blood lipoproteins: the candidate gene approach.

AJ Lusis - Journal of lipid research, 1988 - Elsevier
Family studies have revealed that individual variations in the levels and structures of
lipoproteins in the blood are due in large part to hereditary influences. Since such …

Molecular biology of human apolipoproteins B and E and associated diseases of lipoprotein metabolism

VI Zannis - Advances in lipid research, 1989 - Elsevier
Publisher Summary This chapter discusses the molecular biology of human apolipoproteins
B and E and associated diseases of lipoprotein metabolism. The protein components of …

Genetic defects in lipoprotein metabolism: elevation of atherogenic lipoproteins caused by impaired catabolism

RW Mahley, KH Weisgraber, TL Innerarity, SC Rall - Jama, 1991 - jamanetwork.com
Certain proteins (called apolipoproteins B and E) on the surface of lipoprotein particles are
responsible for mediating the binding of cholesterol-rich particles to specific lipoprotein …

[1] Apolipoproteins: Pathophysiology and clinical implications

W Patsch, AM Gotto Jr - Methods in enzymology, 1996 - Elsevier
Publisher Summary The term apolipoprotein was initially coined by John Oncley to refer to
the protein constituents of plasma lipoproteins. Plasma apolipoproteins are of interest …