From the updated landscape of the emerging biologics for IBDs treatment to the new delivery systems
J Yang, D Li, M Zhang, G Lin, S Hu, H Xu - Journal of Controlled Release, 2023 - Elsevier
Inflammatory bowel diseases (IBDs) treatments have shifted from small-molecular
therapeutics to the oncoming biologics. The first-line biologics against the moderate-to …
therapeutics to the oncoming biologics. The first-line biologics against the moderate-to …
Biologic therapies against inflammatory bowel disease: a dysregulated immune system and the cross talk with gastrointestinal mucosa hold the key
P Dharmani, K Chadee - Current molecular pharmacology, 2008 - ingentaconnect.com
Inflammatory bowel disease (IBD) is a GI tract disorder that manifests as either Ulcerative
colitis (UC) or Crohn's disease (CD). The precise etiology of IBD is still not completely …
colitis (UC) or Crohn's disease (CD). The precise etiology of IBD is still not completely …
[HTML][HTML] Current status of novel biologics and small molecule drugs in the individualized treatment of inflammatory bowel disease
YH Xu, WM Zhu, Z Guo - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
Abstract Treatment strategies for inflammatory bowel disease (IBD) are rapidly evolving with
the development of biologics and small molecule drugs (SMDs). However, these drugs are …
the development of biologics and small molecule drugs (SMDs). However, these drugs are …
[HTML][HTML] Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …
Inflammatory bowel disease: an overview of immune mechanisms and biological treatments
BRR de Mattos, MPG Garcia… - Mediators of …, 2015 - Wiley Online Library
Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the
intestinal tract associated with an imbalance of the intestinal microbiota. Crohn's disease …
intestinal tract associated with an imbalance of the intestinal microbiota. Crohn's disease …
[HTML][HTML] Biological treatments in inflammatory bowel disease: a complex mix of mechanisms and actions
LO Moreno, S Fernández-Tomé, R Abalo - Biologics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic disease that requires lifelong medication and
whose incidence is increasing over the world. There is currently no cure for IBD, and the …
whose incidence is increasing over the world. There is currently no cure for IBD, and the …
[HTML][HTML] The current state of the art for biological therapies and new small molecules in inflammatory bowel disease
S Paramsothy, AK Rosenstein, S Mehandru… - Mucosal …, 2018 - Elsevier
The emergence of biologic therapies is arguably the greatest therapeutic advance in the
care of inflammatory bowel disease (IBD) to date, allowing directed treatments targeted at …
care of inflammatory bowel disease (IBD) to date, allowing directed treatments targeted at …
Overcoming therapeutic obstacles in inflammatory bowel diseases: a comprehensive review on novel drug delivery strategies
Inflammatory bowel diseases (IBDs) are a group of debilitating inflammatory complications
specially inflicting colonic tissue in which full long term remission with current standardized …
specially inflicting colonic tissue in which full long term remission with current standardized …
[HTML][HTML] Classical and recent advances in the treatment of inflammatory bowel diseases
H Sales-Campos, PJ Basso, VBF Alves… - Brazilian Journal of …, 2014 - SciELO Brasil
Crohn's disease (CD) and ulcerative colitis (UC) are intestinal disorders that comprise the
inflammatory bowel diseases (IBD). These disorders have a significant effect on the quality …
inflammatory bowel diseases (IBD). These disorders have a significant effect on the quality …
[HTML][HTML] Perspectives on current and novel treatments for inflammatory bowel disease
SY Na, W Moon - Gut and Liver, 2019 - ncbi.nlm.nih.gov
New therapeutic strategies in inflammatory bowel disease (IBD) have shifted from symptom
control towards treat-to-target algorithms in order to optimize treatment results. The treatment …
control towards treat-to-target algorithms in order to optimize treatment results. The treatment …