Novel biomarkers in membranous nephropathy

Q Liu, J Liu, B Lin, Y Zhang, M Ma, M Yang… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the main cause of adult nephrotic syndrome (NS). The
pathogenesis of MN is complex and involves subepithelial immune complex deposition …

Potential therapeutic targets for membranous nephropathy: proteome-wide Mendelian randomization and colocalization analysis

Z Su, Q Wan - Frontiers in Immunology, 2024 - frontiersin.org
Background The currently available medications for treating membranous nephropathy (MN)
still have unsatisfactory efficacy in inhibiting disease recurrence, slowing down its …

Comprehensive identification of immune-associated biomarkers based on network and mRNA expression patterns in membranous glomerulonephritis

C Zhang, L Leng, X Zhang, Y Zhao, Z Li - Journal of Translational …, 2018 - Springer
Background Membranous glomerulonephritis (MGN) is the most common cause of nephrotic
syndrome in adult patients. Despite extensive evidences suggested that many immune …

Serum metabolomics analysis reveals metabolite profile and key biomarkers of idiopathic membranous nephropathy

M Ye, D Tang, W Li, C Ma, Z Zeng, S Liao, Z Song… - PeerJ, 2023 - peerj.com
Background Idiopathic membranous nephropathy (IMN) is an organ-specific autoimmune
disease with multiple and complex pathogenic mechanisms. Currently, renal biopsy is …

Identification of hub genes and immune-related pathways for membranous nephropathy by bioinformatics analysis

XY Cai, ZF Wang, SW Ge, G Xu - Frontiers in Physiology, 2022 - frontiersin.org
OBJECTIVE: We aim to explore the detailed molecular mechanisms of membrane
nephropathy (MN) related genes by bioinformatics analysis. METHODS: Two microarray …

Podocyte Pathogenic Bone Morphogenetic Protein‐2 Pathway and Immune Cell Behaviors in Primary Membranous Nephropathy

A Cai, Y Meng, H Zhou, H Cai, X Shao… - Advanced …, 2024 - Wiley Online Library
Primary membranous nephropathy (PMN) is one of the leading causes of end‐stage renal
disease, and the most frequent cause of massive proteinuria in nondiabetic adults, resulting …

[PDF][PDF] Biomarkers in primary membranous nephropathy, a guide to precision medicine

M Nafar, N Dalili, S Samavat - Iranian Journal of Kidney Diseases, 2020 - researchgate.net
The diagnosis of membranous nephropathy (MN) as the most common primary
glomerulopathy among non-diabetic adults, 1 already depends on kidney biopsy, an …

Progress on target antigens and molecular biomarkers in membranous nephropathy

C Zige, LI Yi, BAO Hao - Chinese Journal of Nephrology, Dialysis & …, 2023 - njcndt.com
Membranous nephropathy (MN) is a glomerular disease closely associated with immune
system dysregulation. The pathogenic cornerstone of MN lies in the generation of …

Membranous nephropathy in the UK Biobank

P Hamilton, K Blaikie, SA Roberts, M Gittins… - Plos one, 2023 - journals.plos.org
Background Despite MN being one of the most common causes of nephrotic syndrome
worldwide, its biological and environmental determinants are poorly understood in large …

Intrarenal single-cell sequencing of hepatitis b virus associated membranous nephropathy

L Yu, W Lin, C Shen, T Meng, P Jin, X Ding… - Frontiers in …, 2022 - frontiersin.org
To date, the pathogenesis of hepatitis B virus (HBV)-associated membranous nephropathy
(MN) remains elusive. This study aimed to decipher the etiopathogenesis of HBV-associated …