Oxytocin in the socioemotional brain: implications for psychiatric disorders

P Kirsch - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
The neuropeptide oxytocin (OXT), highly conserved during evolution, is an important
modulator of social and emotional processes across many species. During the last decade …

Oxytocin suppresses basal glutamatergic transmission but facilitates activity‐dependent synaptic potentiation in the medial prefrontal cortex

I Ninan - Journal of neurochemistry, 2011 - Wiley Online Library
J. Neurochem.(2011) 119, 324–331. Abstract Both oxytocin and oxytocin receptors are
implicated in neuropsychiatric disorders, particularly autism which involves a severe deficit …

The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis

M Valstad, GA Alvares, M Egknud… - Neuroscience & …, 2017 - Elsevier
There is growing interest in the role of the oxytocin system in social cognition and behavior.
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …

Breaking the loop: oxytocin as a potential treatment for drug addiction

IS McGregor, MT Bowen - Hormones and behavior, 2012 - Elsevier
Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

[HTML][HTML] Elevated salivary levels of oxytocin persist more than 7 h after intranasal administration

MH Van IJzendoorn, R Bhandari… - Frontiers in …, 2012 - frontiersin.org
We addressed the question how long salivary oxytocin levels remain elevated after
intranasal administration, and whether it makes a difference when 16 or 24 IU of oxytocin …

Oxytocin plasma concentrations after single intranasal oxytocin administration–a study in healthy men

A Gossen, A Hahn, L Westphal, S Prinz, RT Schultz… - Neuropeptides, 2012 - Elsevier
The neuropeptide oxytocin has become a subject of great interest in studies investigating
human social cognition. Single intranasal administration of the hormone has been reported …

[HTML][HTML] Oxytocin modulates attention switching between interoceptive signals and external social cues

S Yao, B Becker, W Zhao, Z Zhao, J Kou, X Ma… - …, 2018 - nature.com
Emotional experience involves an integrated interplay between processing of external
emotional cues and interoceptive feedback, and this is impaired in a number of emotional …

The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats

NA Everett, AJ Turner, PA Costa, SJ Baracz… - …, 2021 - nature.com
The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …

Fear-enhancing effects of septal oxytocin receptors

YF Guzmán, NC Tronson, V Jovasevic, K Sato… - Nature …, 2013 - nature.com
The nonapeptide oxytocin is considered beneficial to mental health due to its anxiolytic,
prosocial and antistress effects, but evidence for anxiogenic actions of oxytocin in humans …

[HTML][HTML] Oxytocin's neurochemical effects in the medial prefrontal cortex underlie recovery of task-specific brain activity in autism: a randomized controlled trial

Y Aoki, T Watanabe, O Abe, H Kuwabara… - Molecular …, 2015 - nature.com
The neuropeptide oxytocin may be an effective therapeutic strategy for the currently
untreatable social and communication deficits associated with autism. Our recent paper …