Combination of microRNA therapeutics with small-molecule anticancer drugs: mechanism of action and co-delivery nanocarriers
X Dai, C Tan - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) regulate multiple molecular pathways vital for the hallmarks of cancer
with a high degree of biochemical specificity and potency. By restoring tumor suppressive …
with a high degree of biochemical specificity and potency. By restoring tumor suppressive …
MicroRNA therapeutics in cancer: current advances and challenges
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
Therapeutic prospects of microRNAs in cancer treatment through nanotechnology
R Awasthi, MJ Rathbone, PM Hansbro… - Drug delivery and …, 2018 - Springer
MicroRNAs (miRNAs) represent a new class of diagnostic and prognostic biomarker as well
as new therapeutic targets in cancer therapy. miRNAs are gaining significant interest due to …
as new therapeutic targets in cancer therapy. miRNAs are gaining significant interest due to …
miRacle of microRNA-driven cancer nanotherapeutics
Simple Summary The discovery of microRNAs has revolutionized the world of science and
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …
Nanocarriers for microRNA delivery in cancer medicine
I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
The number of deaths caused by cancer is expected to increase partly due to the lack of
selectivity and undesirable systemic effects of current treatments. Advances in the …
selectivity and undesirable systemic effects of current treatments. Advances in the …
In vivo delivery of miRNAs for cancer therapy: challenges and strategies
Abstract MicroRNAs (miRNAs), small non-coding RNAs, can regulate post-transcriptional
gene expressions and silence a broad set of target genes. miRNAs, aberrantly expressed in …
gene expressions and silence a broad set of target genes. miRNAs, aberrantly expressed in …
Exploiting nanotechnology for the development of microRNA-based cancer therapeutics
MicroRNAs (miRNAs/miRs) represent a novel class of small non-coding RNAs that post-
transcriptionally regulate gene expression by base pairing with complementary sequences …
transcriptionally regulate gene expression by base pairing with complementary sequences …
Applications of nanotechnologies for miRNA-based cancer therapeutics: current advances and future perspectives
LA Bravo-Vázquez, A Méndez-García… - … in Bioengineering and …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are short (18–25 nt), non-coding, widely conserved RNA molecules
responsible for regulating gene expression via sequence-specific post-transcriptional …
responsible for regulating gene expression via sequence-specific post-transcriptional …
miRNA nanotherapeutics for cancer
Highlights•MicroRNAs play a major role in cancer.•Several clinical trials with microRNA are
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …
[HTML][HTML] Modulating microRNAs in cancer: Next-generation therapies
N Arghiani, K Shah - Cancer Biology & Medicine, 2022 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of endogenously expressed non-coding regulators of the
genome with an ability to mediate a variety of biological and pathological processes. There …
genome with an ability to mediate a variety of biological and pathological processes. There …
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