The tremendous success of Staphylococcus aureus as a pathogen is due to the controlled
expression of a diverse array of virulence factors. The effects of host environments on the …

Our previous studies showed that both Sae and Fur are required for the induction of eap and
emp expression in low iron. In this study, we show that expression of sae is also iron …

Staphylococcus aureus pathogenesis is significantly influenced by the iron status of the host.
However, the regulatory impact of host iron sources on S. aureus gene expression remains …

The unique redox potential of iron makes it an ideal cofactor in diverse biochemical
reactions. Iron is therefore vital for the growth and proliferation of nearly all organisms …

Why Staphylococcus aureus, like some other bacterial pathogens, is able to target some
animals and not others remains a puzzle. Recent research provides new insights into …

The use of iron as an enzymatic cofactor is pervasive in biological systems. Consequently
most living organisms, including pathogenic bacteria, require iron to survive and replicate …

Staphylococcus aureus can proliferate in iron-limited environments such as the mammalian
host. The transcriptional profiles of 460 genes (iron-regulated, putative Fur-regulated …

Iron is an essential nutrient for the survival and pathogenesis of bacteria, but relatively little
is known regarding its transport and regulation in staphylococci. Based on the known …

The Staphylococcus aureus genome encodes three ferric uptake regulator (Fur)
homologues: Fur, PerR, and Zur. To determine the exact role of PerR, we inactivated the …

Staphylococcus aureus is a prominent nosocomial pathogen and a major cause of
biomaterial-associated infections. The success of S. aureus as a pathogen is due in part to …