Endothelial dysfunction is the common molecular basis of multiple human diseases, such as
atherosclerosis, diabetes, hypertension, and acute lung injury. Therefore, primary isolation …

Pulmonary microvascular endothelial cells (ECs) are integral to the alveoli-capillary barrier
of the lung. The EC barrier integrity is known to be disrupted in severe lung diseases such …

Endothelial cells provide a useful research model in many areas of vascular biology. Since
its first isolation 1, human umbilical vein endothelial cells (HUVECs) have shown to be …

Several protocols for the isolation of endothelial cells (ECs) from murine lung have been
described in the literature. We, however, encountered a number of problems while using …

EC culture models are essential to study pathological alterations of endothelial cells (ECs) in
pulmonary vascular diseases under standardized conditions. Nevertheless, little is known …

Background: Cellular diversity of the lung endothelium has not been systematically
characterized in humans. We provide a reference atlas of human lung endothelial cells …

Endothelial barrier dysfunction is an important contributor to the pathogenesis of acute lung
injury (ALI) and acute respiratory distress syndrome (ARDS). Even though approaches that …

Endothelial cells (ECs) from the small intestine, colon, liver, and heart have distinct
phenotypes and functional adaptations that are dependent on their physiological …

The formation of blood vessel networks is a fundamental event in vertebrate embryo
development. Angiogenesis and vasculogenesis are the essential processes in vascular …

Microvascular endothelial cells (MVEC), which differ from large vessel endothelial cells,
have been isolated successfully from lungs of various species, including man. However …