In recent decades, many efforts have been made in order to improve drug bioavailability
after oral administration. Gastroretentive drug delivery systems are a good example; they …

Background: Drugs having absorption window in the stomach or upper small intestine have
restricted bioavailability with conventional dosage forms. The gastric residence time of these …

The success of controlled oral drug deliveries is associated with some physiological
adversities like short gastric residence time and unpredictable gastric emptying time …

In recent years, many attempts have been made to enhance the drug bioavailability and
therapeutic effectiveness of oral dosage forms. In this context, various gastroretentive drug …

Oral delivery of the drug is by far the most preferable route of drug delivery due to the ease
of administration, patient compliance and flexibility in the formulations but has a drawback of …

Gastro-retentive drug delivery systems are some of the best technologies delivered through
oral route. These mainly came into picture for their effective local action in the GI region …

A major constraint in oral controlled release drug delivery is that not all the drug candidates
are absorbed uniformly throughout the gastrointestinal tract (GIT). Drugs having “absorption …

Introduction: In recent years, various technological improvements have been achieved and
new concepts have been developed, in the area of controlled release solid oral dosage …

In the present era, gastroretentive dosage forms (GRDF) receive great attention because
they can improve the performance of controlled release systems. An optimum GRDF system …

Various attempts have been made to develop gastroretentive delivery systems. For example,
floating, swelling, mucoadhesive, and high‐density systems have been developed to …