Identification of potential lncRNAs and miRNAs as diagnostic biomarkers for papillary thyroid carcinoma based on machine learning

F Yang, J Zhang, B Li, Z Zhao, Y Liu… - International Journal …, 2021 - Wiley Online Library
Background. Papillary thyroid carcinoma (PTC) accounts for most of the proportion of thyroid
cancer (TC). The objective of this study was to identify diagnostic, differentially expressed …

A network-based approach to identify molecular signatures and comorbidities of thyroid cancer

M Ali Hossain, TA Asa, F Huq, JMW Quinn… - … of International Joint …, 2020 - Springer
The molecular mechanisms driving thyroid cancer (TC) development and progression are
poorly understood, but identifying molecular pathways and hub genes abnormally active in …

Identification and validation of an immune-related prognostic signature and key gene in papillary thyroid carcinoma

R Qin, C Li, X Wang, Z Zhong, C Sun - Cancer Cell International, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the most common pathological type of
thyroid cancer. The effect of traditional anti-tumor therapy is not ideal for the patients with …

Identification of a five-gene signature and establishment of a prognostic nomogram to predict progression-free interval of papillary thyroid carcinoma

M Wu, H Yuan, X Li, Q Liao, Z Liu - Frontiers in endocrinology, 2019 - frontiersin.org
Background: The incidence of papillary thyroid carcinoma (PTC) is high and increasing
worldwide. Although prognosis is relatively good, it is important to select the minority of …

Mapping the molecular basis and markers of papillary thyroid carcinoma progression and metastasis using global transcriptome and microRNA profiling

OZ Akyay, E Gov, H Kenar, KY Arga… - OMICS: A Journal of …, 2020 - liebertpub.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer (TC). In a
subgroup of patients with PTC, the disease progresses to an invasive stage or in some …

Transcriptome analysis discloses dysregulated genes in normal appearing tumor-adjacent thyroid tissues from patients with papillary thyroid carcinoma

H He, S Liyanarachchi, W Li, DF Comiskey Jr, P Yan… - Scientific Reports, 2021 - nature.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. The molecular
characteristics of histologically normal appearing tissue adjacent to the tumor (NAT) from …

Meta-analysis of microarray datasets identify several chromosome segregation-related cancer/testis genes potentially contributing to anaplastic thyroid carcinoma

M Liu, Y Qiu, T Jin, Y Zhou, Z Mao, Y Zhang - PeerJ, 2018 - peerj.com
Aim Anaplastic thyroid carcinoma (ATC) is the most lethal thyroid malignancy. Identification
of novel drug targets is urgently needed. Materials & Methods We re-analyzed several GEO …

In‐depth proteomics analysis to identify biomarkers of papillary thyroid cancer patients older than 45 Years with different degrees of lymph node metastases

S Zhan, T Wang, M Wang, J Li… - Proteomics–Clinical …, 2019 - Wiley Online Library
Purpose Investigations of the molecular mechanisms underlying the metastatic phenotype of
papillary thyroid cancer (PTC) and identification of novel candidate biomarkers to better …

Molecular characterization of papillary thyroid carcinoma: a potential three-lncRNA prognostic signature

X You, S Yang, J Sui, W Wu, T Liu, S Xu… - Cancer management …, 2018 - Taylor & Francis
Purpose Papillary thyroid carcinoma (PTC), the most frequent type of malignant thyroid
tumor, lacks novel and reliable biomarkers of patients' prognosis. In the current study, we …

Prediction of novel target genes and pathways involved in tall cell variant papillary thyroid carcinoma

F Xia, B Jiang, Y Chen, X Du, Y Peng, W Wang… - Medicine, 2018 - journals.lww.com
Background: Tall cell variant papillary thyroid carcinoma (TCPTC) is reportedly associated
with aggressive clinicopathological parameters and poor outcomes; however, the molecular …