Despite extensive effort, only a few chronic obstructive pulmonary disease (COPD)-
associated genes have been suggested, indicating that there must be additional risk …

Activation of the cyclic AMP (cAMP) signaling pathway leads to the suppression of
inflammation in the airways and relaxation of airway smooth muscle. Intracellular cAMP …

ABSTRACT Superoxide dismutase-3 (SOD3) is a major extracellular antioxidant enzyme,
and previous studies have indicated a possible role of this gene in chronic obstructive …

Background It is known that the contribution of risk alleles to chronic obstructive pulmonary
disease (COPD) may vary between populations. Further, previous studies involving various …

Background Identifying the genetic basis of airflow limitation is one of the most interesting
issues for understanding chronic obstructive pulmonary disease (COPD) pathophysiology …

Background To identify COPD associated gene susceptibility and lung function in a
longitudinal cohort including COPD and subjects who were at risk for developing COPD …

Background Chronic obstructive pulmonary disease (COPD) is influenced by both
environmental and genetic factors. Few gene studies of the Chinese population have …

Background Chronic obstructive pulmonary disease (COPD) is a chronic bronchitis (or)
emphysema with a high disability and fatality rate. This study aimed to explore the …

Background: Genetic association studies have identified single nucleotide polymorphisms
(SNPs) associated with lasting lung diseases such as Chronic Obstructive Pulmonary …

Genome-wide linkage analysis in the Boston Early-Onset Chronic Obstructive Pulmonary
Disease (COPD) Study has demonstrated significant evidence of linkage to chromosome 8p …