Studies using genetic isolates with limited genetic variation may be useful in chronic
obstructive pulmonary disease (COPD) genetics, but are thus far lacking. The associations …

Heterogeneity of lung function levels and risk for developing chronic obstructive pulmonary
disease (COPD) among people exposed to the same environmental risk factors, such as …

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of mortality
worldwide. Recent genome-wide association studies (GWAS) have identified robust …

We examined the association between single-nucleotide polymorphisms (SNPs) previously
associated with chronic obstructive pulmonary disease (COPD) and/or lung function with …

Background Hypoxemia, hypercarbia, and pulmonary arterial hypertension are known
complications of advanced COPD. We sought to identify genetic polymorphisms associated …

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide.
We performed a genetic association study in 15,256 cases and 47,936 controls, with …

Chronic obstructive pulmonary disease (COPD) is a complex disease with multifactorial
background, based on the interaction of environmental and genetic factors. Environmental …

Abstract Chronic Obstructive Pulmonary Disease (COPD) has a simple physiological
diagnostic criterion but a wide range of clinical characteristics. The mechanisms underlying …

Background. Last two decades, many association studies on genetic variants and chronic
obstructive pulmonary disease (COPD) risk have been published. But results from different …

The genetic component was suggested to contribute to the development of chronic
obstructive pulmonary disease (COPD), a major and growing public health burden. The …