Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1
There is evidence of a hereditary component in chronic obstructive pulmonary disease
(COPD). A number of genetic association studies have been performed to find susceptibility …
(COPD). A number of genetic association studies have been performed to find susceptibility …
Effects of Lung Function-Related Genes and TSLP on COPD Phenotypes
H Yamada, N Hida, H Masuko… - COPD: Journal of …, 2020 - Taylor & Francis
A weighted genetic risk score (GRS) based on 16 SNPs implicated in reduced lung function
in both Japanese and non-Japanese populations was previously associated with the onset …
in both Japanese and non-Japanese populations was previously associated with the onset …
Associations of genetic risk and smoking with incident COPD
Background Genetic factors and smoking contribute to chronic obstructive pulmonary
disease (COPD), but whether a combined polygenic risk score (PRS) is associated with …
disease (COPD), but whether a combined polygenic risk score (PRS) is associated with …
Absence of association between SERPINE2genetic polymorphisms and chronic obstructive pulmonary disease in Han Chinese: a case-control cohort study
L Zhong, WP Fu, C Sun, LM Dai, YP Zhang - BMC Medical Genetics, 2009 - Springer
Background Recent studies have proposed that the serine protease inhibitor E2
(SERPINE2) was a novel susceptibility gene for chronic obstructive pulmonary disease …
(SERPINE2) was a novel susceptibility gene for chronic obstructive pulmonary disease …
RETRACTED ARTICLE: Relationships of COX2 and MMP12 genetic polymorphisms with chronic obstructive pulmonary disease risk: a meta-analysis
XL Yu, J Zhang, F Zhao, XM Pan - Molecular biology reports, 2014 - Springer
We performed the present meta-analysis in an attempt to confirm the correlation of genetic
polymorphisms in the COX2 and MMP12 genes with the susceptibility to chronic obstructive …
polymorphisms in the COX2 and MMP12 genes with the susceptibility to chronic obstructive …
Association of FAM13A polymorphisms with COPD and COPD-related phenotypes in Han Chinese
B Wang, B Liang, J Yang, J Xiao, C Ma, S Xu, J Lei… - Clinical …, 2013 - Elsevier
Objectives Genome-wide association studies (GWAS) and integrative genomics approaches
have demonstrated significant associations between chronic obstructive pulmonary disease …
have demonstrated significant associations between chronic obstructive pulmonary disease …
Genetic epidemiology of COPD (COPDGene) study design
EA Regan, JE Hokanson, JR Murphy… - COPD: Journal of …, 2011 - Taylor & Francis
Background: COPDGene is a multicenter observational study designed to identify genetic
factors associated with COPD. It will also characterize chest CT phenotypes in COPD …
factors associated with COPD. It will also characterize chest CT phenotypes in COPD …
Genetic determinants of functional impairment in chronic obstructive pulmonary disease
Rationale: Patients with severe chronic obstructive pulmonary disease (COPD) may have
varying levels of disability despite similar levels of lung function. This variation may reflect …
varying levels of disability despite similar levels of lung function. This variation may reflect …
What do polymorphisms tell us about the mechanisms of COPD?
COPD (chronic obstructive pulmonary disease) is characterized by irreversible lung airflow
obstruction. Cigarette smoke is the major risk factor for COPD development. However, only a …
obstruction. Cigarette smoke is the major risk factor for COPD development. However, only a …
[HTML][HTML] Chronic obstructive pulmonary disease genetics: a review of the past and a look into the future
M Hardin, EK Silverman - Chronic Obstructive Pulmonary Diseases …, 2014 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) affects over 10 million Americans. 1 This
complex disorder demonstrates many different presentations in a wide variety of patients …
complex disorder demonstrates many different presentations in a wide variety of patients …