Formulation and optimization of lacidipine loaded niosomal gel for transdermal delivery: in-vitro characterization and in-vivo activity
The aim of the present research work is to formulate lacidipine (LAC) loaded niosomes
formulation for the management of hypertension by thin film hydration technique. The …
formulation for the management of hypertension by thin film hydration technique. The …
Novel non-ionic surfactant proniosomes for transdermal delivery of lacidipine: optimization using 23 factorial design and in vivo evaluation in rabbits
SM Soliman, NS Abdelmalak, ON El-Gazayerly… - Drug …, 2016 - Taylor & Francis
Context: Proniosomes offer a versatile vesicle drug delivery concept with potential for
delivery of drugs via transdermal route. Objectives: To develop proniosomal gel using …
delivery of drugs via transdermal route. Objectives: To develop proniosomal gel using …
A novel transdermal nanoethosomal gel of lercanidipine HCl for treatment of hypertension: optimization using Box-Benkhen design, in vitro and in vivo …
HF Salem, SF El-Menshawe, RA Khallaf… - Drug delivery and …, 2020 - Springer
Poor bioavailability of drugs via oral route is the greatest challenge facing drug formulation.
To overcome this obstacle, transdermal route was commonly used as an alternative route to …
To overcome this obstacle, transdermal route was commonly used as an alternative route to …
Formulation of niosomal gel for enhanced transdermal lopinavir delivery and its comparative evaluation with ethosomal gel
KK Patel, P Kumar, HP Thakkar - AAPS pharmscitech, 2012 - Springer
The aim was to develop niosomal gel as a transdermal nanocarrier for improved systemic
availability of lopinavir. Niosomes were prepared using thin-film hydration method and …
availability of lopinavir. Niosomes were prepared using thin-film hydration method and …
Investigating superiority of novel bilosomes over niosomes in the transdermal delivery of diacerein: in vitro characterization, ex vivo permeation and in vivo skin …
DE Aziz, AA Abdelbary, AI Elassasy - Journal of liposome research, 2019 - Taylor & Francis
Skin is considered the most accessible organ of the body because of its underlying capillary
network. However, stratum corneum (SC), the upper most layer of skin, represents major …
network. However, stratum corneum (SC), the upper most layer of skin, represents major …
Diacerein niosomal gel for topical delivery: development, in vitro and in vivo assessment
KM El-Say, FI Abd-Allah, AE Lila… - Journal of liposome …, 2016 - Taylor & Francis
The purpose of this study was to load diacerein (DCR) in niosomes by applying response
surface methodology and incorporate these niosomes in gel base for topical delivery. Box …
surface methodology and incorporate these niosomes in gel base for topical delivery. Box …
[PDF][PDF] Evaluation of different compositions of niosomes to optimize aceclofenac transdermal delivery
AB Solanki, JR Parikh, RH Parikh… - Asian journal of …, 2010 - academia.edu
Purpose: To optimize the composition of niosomes containing aceclofenac for transdermal
application, with a view to improve permeation of drug during an extended period of time …
application, with a view to improve permeation of drug during an extended period of time …
Innovative topical niosomal gel formulation containing diclofenac sodium (niofenac)
The purpose of this research was to enhance the transdermal delivery of diclofenac sodium
niosomal formulations. To characterise the obtained niosomes, SEM, XRPD, DSC and ATR …
niosomal formulations. To characterise the obtained niosomes, SEM, XRPD, DSC and ATR …
Investigating the potential of utilizing glycerosomes as a novel vesicular platform for enhancing intranasal delivery of lacidipine
Lacidipine is a potent dihydropyridine calcium channel blocker used for management of
hypertension and atherosclerosis. The drug has low and fluctuating oral bioavailability …
hypertension and atherosclerosis. The drug has low and fluctuating oral bioavailability …
A novel vesicular transdermal delivery of nifedipine – preparation, characterization and in vitro/in-vivo evaluation
Nifedipine is a calcium channel blocker extensively used in the treatment of anginal and
hypertension. On oral administration it undergoes extensive first pass metabolism, which …
hypertension. On oral administration it undergoes extensive first pass metabolism, which …