Keeping it organized: multicompartment constructs to mimic tissue heterogeneity

A Sanchez‐Rubio, V Jayawarna… - Advanced …, 2023 - Wiley Online Library
Tissue engineering aims at replicating tissues and organs to develop applications in vivo
and in vitro. In vivo, by engineering artificial constructs using functional materials and cells to …

Emerging biomaterials and technologies to control stem cell fate and patterning in engineered 3D tissues and organoids

M Farahani, J Carthew, S Bhowmik, C Shard… - …, 2022 - pubs.aip.org
The ability to create complex three-dimensional cellular models that can effectively replicate
the structure and function of human organs and tissues in vitro has the potential to …

[HTML][HTML] Four-dimensional bioprinting as a new era for tissue engineering and regenerative medicine

P Morouço, W Lattanzi, N Alves - Frontiers in Bioengineering and …, 2017 - frontiersin.org
In the era of “big data,” coping with a society that is in constant development, the discovery of
“new” scientific and technological knowledge must (i) progress at an incredibly fast pace,(ii) …

Bridging the gap: from 2D cell culture to 3D microengineered extracellular matrices

Y Li, KA Kilian - Advanced healthcare materials, 2015 - Wiley Online Library
Historically the culture of mammalian cells in the laboratory has been performed on planar
substrates with media cocktails that are optimized to maintain phenotype. However, it is …

3D bioprinting: novel approaches for engineering complex human tissue equivalents and drug testing

J Hagenbuchner, D Nothdurfter… - Essays in …, 2021 - portlandpress.com
Conventional approaches in drug development involve testing on 2D-cultured mammalian
cells, followed by experiments in rodents. Although this is the common strategy, it has …

Bio-inspired 3D microenvironments: a new dimension in tissue engineering

CM Magin, DL Alge, KS Anseth - Biomedical Materials, 2016 - iopscience.iop.org
Biomaterial scaffolds have been a foundational element of the tissue engineering paradigm
since the inception of the field. Over the years there has been a progressive move toward …

Three-dimensional bioprinting of anatomically realistic tissue constructs for disease modeling and drug testing

NI Moldovan - Tissue Engineering Part C: Methods, 2021 - liebertpub.com
Three-dimensional (3D) bioprinting is an emerging tissue engineering technology, already
with several remarkable accomplishments and with more promises to fulfill. Besides the …

[PDF][PDF] 3D Bioprinting of Functional Tissue Models

M Tang, S You, J Sun, W Zhu, S Chen - BIOPRINTING - sigmaaldrich.cn
The emergence of new technologies in tissue engineering and regenerative medicine
promises to make a number of previously impossible applications a reality, such as …

Biofabrication strategies for engineering heterogeneous artificial tissues

P Ambhorkar, RH Rakin, Z Wang, H Kumar, K Kim - Additive Manufacturing, 2020 - Elsevier
The persistent shortage of donor-organs for transplantation and accurate tissue models for
disease study has resulted in a high demand for artificial tissues and organs. The field of …

Multimaterial, heterogeneous, and multicellular three-dimensional bioprinting

C De Maria, G Vozzi, L Moroni - Mrs Bulletin, 2017 - cambridge.org
Bioprinting promises to create three-dimensional in vitro models to study pathological states
and possible new therapies, and in the future, to produce complex tissue and organ …