A novel pH-sensitive hydrogel composed of N, O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery

SC Chen, YC Wu, FL Mi, YH Lin, LC Yu… - Journal of controlled …, 2004 - Elsevier
A novel pH-sensitive hydrogel system composed of a water-soluble chitosan derivative (N, O-
carboxymethyl chitosan, NOCC) and alginate blended with genipin was developed for …

Genipin-crosslinked casein hydrogels for controlled drug delivery

F Song, LM Zhang, C Yang, L Yan - International journal of pharmaceutics, 2009 - Elsevier
Recent advances in hydrogel technology have focused on finding more biocompatible, non-
toxic materials intended for pharmaceutical and biomedical applications. In this study …

pH-sensitive interpenetrating network hydrogels based on chitosan derivatives and alginate for oral drug delivery

J Yang, J Chen, D Pan, Y Wan, Z Wang - Carbohydrate polymers, 2013 - Elsevier
Methoxy poly (ethylene glycol) grafted carboxymethyl chitosan (mPEG-g-CMC) and alginate
were chosen as the constituents of hydrogel beads for the construction of an interpenetrating …

A novel pH-sensitive hydrogel based on dual crosslinked alginate/N-α-glutaric acid chitosan for oral delivery of protein

R Gong, C Li, S Zhu, Y Zhang, Y Du, J Jiang - Carbohydrate polymers, 2011 - Elsevier
A novel pH-sensitive hydrogel based on dual crosslinked alginate/N-α-glutaric acid chitosan
(GAC) was prepared. The homogeneous alginate/GAC solution was dropped into calcium …

Injectable biopolymer based hydrogels for drug delivery applications

S Atta, S Khaliq, A Islam, I Javeria, T Jamil… - International journal of …, 2015 - Elsevier
Biopolymer based pH-sensitive hydrogels were prepared using chitosan (CS) with
polyethylene glycol (PEG) of different molecular weights in the presence of silane …

Dual cross-linked chitosan/alginate hydrogels prepared by Nb-Tz 'click'reaction for pH responsive drug delivery

HT Hoang, TT Vu, V Karthika, SH Jo, YJ Jo… - Carbohydrate …, 2022 - Elsevier
A novel physically and chemically double-crosslinked hydrogel derived from chitosan
oligosaccharide/alginate (COS/Alg) was developed by using norbornene (Nb)-tetrazine (Tz) …

Preparation and characterization of IPN hydrogels composed of chitosan and gelatin cross-linked by genipin

L Cui, J Jia, Y Guo, Y Liu, P Zhu - Carbohydrate polymers, 2014 - Elsevier
The interpenetrating polymer networks (IPN) hydrogels based on chitosan and gelatin using
genipin as the cross-linker were prepared and characterized. The IPN formation of the …

Physically crosslinked alginate/N, O-carboxymethyl chitosan hydrogels with calcium for oral delivery of protein drugs

YH Lin, HF Liang, CK Chung, MC Chen, HW Sung - Biomaterials, 2005 - Elsevier
In the study, a complex composed of alginate blended with a water-soluble chitosan (N, O-
carboxymethyl chitosan, NOCC) was prepared to form microencapsulated beads by …

Development of a novel pH sensitive silane crosslinked injectable hydrogel for controlled release of neomycin sulfate

S Jabeen, A Islam, A Ghaffar, N Gull, A Hameed… - International journal of …, 2017 - Elsevier
Silane crosslinked biopolymer based novel pH-responsive hydrogels were fabricated by
blending the cationic (chitosan) and anionic (alginate) polymers with poly (vinyl alcohol) …

Comparative evaluation for controlling release of niacin from protein-and cellulose-chitosan based hydrogels

DH Hanna, VF Lotfy, AH Basta, GR Saad - International journal of biological …, 2020 - Elsevier
This work deals with assessing the efficient performance of sodium caseinate (SC) as
protein-based drug delivery system of niacin (NA) than carboxymethyl cellulose (CMC). In …