Sepsis is defined as a life‐threatening disease involving multiple organ dysfunction caused
by dysregulated host responses to infection. To date, sepsis remains a dominant cause of …

Sepsis, a life-threatening organ dysfunction caused by a dysregulated host response to
infection, is a leading cause of death in intensive care units. The development of sepsis …

Programmed cell death has crucial roles in the physiological maturation of an organism, the
maintenance of metabolism, and disease progression. Pyroptosis, a form of programmed …

Sepsis is recognized as a life‐threatening organ dysfunctional disease that is caused by
dysregulated host responses to infection. Up to now, sepsis still remains a dominant cause …

Pyroptosis, which is characterized by gasdermin family protein‐mediated pore formation,
cellular lysis and the release of pro‐inflammatory cytokines, is a form of programmed cell …

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. Recently was been found that pyroptosis is a unique form of …

Pyroptosis, an inflammatory form of programmed cell death, is the initiating event of sepsis
and results in immune imbalance by releasing IL‐1β and IL‐18 in the early stages. Studies …

The inflammatory response is one of the host's mechanisms to combat pathogens. Normal
and controlled inflammation can accelerate the clearance of pathogens. However, in sepsis …

Pyroptosis is a process of programmed cell death mediated by gasdermin (GSDM) found in
recent years. In the process of pyroptosis, caspase-1 or caspase-11/4/5 is activated, which …

Pyroptosis is a lytic and inflammatory type of programmed cell death that is usually triggered
by inflammasomes and executed by gasdermin proteins. The main characteristics of …