Advances in coronary imaging are needed to enable the early detection of plaque segments
considered to be'vulnerable'for causing clinical events. Pathological studies have …

Coronary artery disease is the result of atherosclerotic changes to the coronary arterial wall,
comprising endothelial dysfunction, vascular inflammation and deposition of lipid-rich …

The majority of coronary atherothrombotic events presenting as myocardial infarction (MI)
occur as a result of plaque rupture or erosion. Understanding the evolution from a stable …

Evidence from the first prospective studies of coronary atherosclerosis demonstrated that
intravascular imaging has limited accuracy in detecting lesions that are likely to progress …

Atherosclerotic plaques prone to rupture may cause acute myocardial infarction (MI) but can
also heal without causing an event. Certain common histopathological features, including …

Early identification of high-risk or vulnerable atherosclerotic plaques prone to rupture and
performing preemptive therapy prior to catastrophic cardiovascular events are optimal goals …

The term “vulnerable plaque” is commonly used to refer to an atherosclerotic plaque that is
prone to rupture and the formation of thrombosis, which can lead to several cardiovascular …

Several studies have been carried out on vulnerable plaque as the main culprit for
ischaemic cardiac events. Historically, the most important diagnostic technique for studying …

Acute coronary syndromes are a spectrum of clinical presentations with various
pathophysiology substrates. As such it is impossible to talk about one type of atherosclerotic …

Coronary heart disease (CHD) remains the leading cause of death in the United States, and
an estimated 1.4 million Americans have a heart attack each year. Over the past 2 decades …