In vivo imaging of tau pathology will provide new insights into tau deposition in the human
brain, thus facilitating research into causes, diagnosis and treatment of major dementias …

The military conflicts of the last decade have highlighted the growing problem of traumatic
brain injury in combatants returning from the battlefield. The considerable evidence pointing …

Highlights•A deeper insight into tau deposition in primary and secondary tauopathies.•Cross-
sectional and longitudinal assessment of the patterns of tau deposition.•A better …

Aggregated tau protein is a major neuropathological substrate central to the
pathophysiology of neurodegenerative diseases such as Alzheimer's disease (AD) …

In vivo imaging of the tau protein has the potential to aid in quantitative diagnosis of
Alzheimer's disease, corroborate or dispute the amyloid hypothesis, and demonstrate …

Pathological cerebral aggregations of proteins are suggested to play a crucial role in the
development of neurodegenerative disorders. For example, aggregation of the protein ß …

Use of selective in-vivo tau imaging will enable improved understanding of tau aggregation
in the brain, facilitating research into causes, diagnosis, and treatment of major tauopathies …

Tau-bearing neurofibrillary lesions present a promising biomarker for premortem diagnosis
and staging of Alzheimer's disease and certain forms of frontotemporal lobar degeneration …

Abnormal aggregation of tau in the brain is a major contributing factor in various
neurodegenerative diseases. The role of tau phosphorylation in the pathophysiology of …

Purpose Depositions of tau fibrils are implicated in diverse neurodegenerative disorders,
including Alzheimer's disease, and precise assessments of tau pathologies and their …