[HTML][HTML] Cutaneous leishmaniasis induces a transmissible dysbiotic skin microbiota that promotes skin inflammation

C Gimblet, JS Meisel, MA Loesche, SD Cole… - Cell host & …, 2017 - cell.com
Skin microbiota can impact allergic and autoimmune responses, wound healing, and anti-
microbial defense. We investigated the role of skin microbiota in cutaneous leishmaniasis …

Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis

TP Singh, C Farias Amorim, VM Lovins… - Journal of Experimental …, 2023 - rupress.org
Cutaneous leishmaniasis causes alterations in the skin microbiota, leading to pathologic
immune responses and delayed healing. However, it is not known how these microbiota …

[HTML][HTML] Microbiota instruct IL-17A-producing innate lymphoid cells to promote skin inflammation in cutaneous leishmaniasis

TP Singh, AM Carvalho, LA Sacramento… - PLoS …, 2021 - journals.plos.org
Innate lymphoid cells (ILCs) comprise a heterogeneous population of immune cells that
maintain barrier function and can initiate a protective or pathological immune response upon …

The influence of skin microorganisms on cutaneous immunity

Y Belkaid, S Tamoutounour - Nature Reviews Immunology, 2016 - nature.com
The skin is a complex and dynamic ecosystem that is inhabited by many microorganisms.
Recent evidence highlights the profound reliance of the skin immune system on its resident …

[HTML][HTML] Evolving approaches to profiling the microbiome in skin disease

Y Chen, R Knight, RL Gallo - Frontiers in Immunology, 2023 - frontiersin.org
Despite its harsh and dry environment, human skin is home to diverse microbes, including
bacteria, fungi, viruses, and microscopic mites. These microbes form communities that may …

[HTML][HTML] Resistance Against Leishmania major Infection Depends on Microbiota-Guided Macrophage Activation

ME Lopes, LM Dos Santos, D Sacks, LQ Vieira… - Frontiers in …, 2021 - frontiersin.org
Innate immune cells present a dual role during leishmaniasis: they constitute the first line of
host defense but are also the main host cells for the parasite. Response against the infection …

Novel mechanisms of microbial crosstalk with skin innate immunity

M Chinnappan, TA Harris‐Tryon - Experimental Dermatology, 2021 - Wiley Online Library
Skin is an organ with a dynamic ecosystem that harbours pathogenic and commensal
microbes, which constantly communicate amongst each other and with the host immune …

[HTML][HTML] Mechanisms of microbe-immune system dialogue within the skin

N Lunjani, S Ahearn-Ford, FS Dube, C Hlela… - Genes & …, 2021 - nature.com
The prevalence and severity of dermatological conditions such as atopic dermatitis have
increased dramatically during recent decades. Many of the factors associated with an …

Recent advances in understanding the role of the skin microbiome in the treatment of atopic dermatitis

K Kim, H Jang, E Kim, H Kim… - Experimental …, 2023 - Wiley Online Library
The skin is the largest organ in the human body, and histologically consists of the epidermis,
dermis and subcutaneous tissue. Humans maintain a cooperative symbiotic relationship …

[HTML][HTML] Commensal microbiota modulate gene expression in the skin

JS Meisel, G Sfyroera, C Bartow-McKenney, C Gimblet… - Microbiome, 2018 - Springer
Background The skin harbors complex communities of resident microorganisms, yet little is
known of their physiological roles and the molecular mechanisms that mediate cutaneous …