The skin microbiome: Associations between altered microbial communities and disease

LS Weyrich, S Dixit, AG Farrer… - Australasian journal …, 2015 - Wiley Online Library
A single square centimetre of the human skin can contain up to one billion microorganisms.
These diverse communities of bacteria, fungi, mites and viruses can provide protection …

[HTML][HTML] Mechanisms for control of skin immune function by the microbiome

T Nakatsuji, JY Cheng, RL Gallo - Current opinion in immunology, 2021 - Elsevier
The skin represents the largest area for direct contact between microbes and host
immunocytes and is a site for constant communication between the host and this diverse …

[HTML][HTML] Genome-wide mapping of gene–microbiota interactions in susceptibility to autoimmune skin blistering

G Srinivas, S Möller, J Wang, S Künzel… - Nature …, 2013 - nature.com
Susceptibility to chronic inflammatory diseases is determined by immunogenetic and
environmental risk factors. Resident microbial communities often differ between healthy and …

Dynamic role of host stress responses in modulating the cutaneous microbiome: implications for wound healing and infection

CJ Holmes, JK Plichta, RL Gamelli… - Advances in wound …, 2015 - liebertpub.com
Significance: Humans are under constant bombardment by various stressors, including
psychological anxiety and physiologic injury. Understanding how these stress responses …

The dynamic balance of the skin microbiome across the lifespan

EC Townsend, LR Kalan - Biochemical Society Transactions, 2023 - portlandpress.com
For decades research has centered on identifying the ideal balanced skin microbiome that
prevents disease and on developing therapeutics to foster this balance. However, this single …

[HTML][HTML] Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation

Y Ito, T Sasaki, Y Li, T Tanoue, Y Sugiura, AN Skelly… - Cell reports, 2021 - cell.com
Host-microbe interactions orchestrate skin homeostasis, the dysregulation of which has
been implicated in chronic inflammatory conditions such as atopic dermatitis and psoriasis …

[HTML][HTML] Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive

DE Sanin, CT Prendergast, CD Bourke… - PLoS …, 2015 - journals.plos.org
The skin provides an important first line of defence and immunological barrier to invasive
pathogens, but immune responses must also be regulated to maintain barrier function and …

[HTML][HTML] Skin dysbiosis in the microbiome in atopic dermatitis is site-specific and involves bacteria, fungus and virus

RD Bjerre, JB Holm, A Palleja, J Sølberg, L Skov… - BMC microbiology, 2021 - Springer
Background Microbial dysbiosis with increased Staphylococcus aureus (S. aureus)
colonization on the skin is a hallmark of atopic dermatitis (AD), however most microbiome …

Skin biomes

N Fyhrquist, A Salava, P Auvinen… - Current allergy and asthma …, 2016 - Springer
The cutaneous microbiome has been investigated broadly in recent years and some
traditional perspectives are beginning to change. A diverse microbiome exists on human …

Structure and function of the human skin microbiome

NN Schommer, RL Gallo - Trends in microbiology, 2013 - cell.com
An abundant and diverse collection of bacteria, fungi, and viruses inhabits the human skin.
These microorganisms vary between individuals and between different sites on the skin. The …