[HTML][HTML] The expanding implications of polyploidy

KP Schoenfelder, DT Fox - The Journal of cell biology, 2015 - ncbi.nlm.nih.gov
Polyploid cells, which contain more than two genome copies, occur throughout nature.
Beyond well-established roles in increasing cell size/metabolic output, polyploidy can also …

Polyploidy: a biological force from cells to ecosystems

DT Fox, DE Soltis, PS Soltis, TL Ashman… - Trends in Cell …, 2020 - cell.com
Polyploidy, resulting from the duplication of the entire genome of an organism or cell, greatly
affects genes and genomes, cells and tissues, organisms, and even entire ecosystems …

Solving the polyploid mystery in health and disease

KJ Gjelsvik, R Besen-McNally, VP Losick - Trends in Genetics, 2019 - cell.com
Polyploidy (the more than doubling of a cell's genome) frequently arises during
organogenesis, tissue repair, and age-associated diseases. Despite its prevalence, major …

Polyploidy in tissue homeostasis and regeneration

JI Øvrebø, BA Edgar - Development, 2018 - journals.biologists.com
Polyploid cells, which contain multiple copies of the typically diploid genome, are
widespread in plants and animals. Polyploidization can be developmentally programmed or …

The evolutionary significance of polyploidy

Y Van de Peer, E Mizrachi, K Marchal - Nature Reviews Genetics, 2017 - nature.com
Polyploidy, or the duplication of entire genomes, has been observed in prokaryotic and
eukaryotic organisms, and in somatic and germ cells. The consequences of polyploidization …

Polyploidy as a fundamental phenomenon in evolution, development, adaptation and diseases

OV Anatskaya, AE Vinogradov - International Journal of Molecular …, 2022 - mdpi.com
DNA replication during cell proliferation is 'vertical'copying, which reproduces an initial
amount of genetic information. Polyploidy, which results from whole-genome duplication, is …

Somatic polyploidy promotes cell function under stress and energy depletion: evidence from tissue-specific mammal transcriptome

OV Anatskaya, AE Vinogradov - Functional & integrative genomics, 2010 - Springer
Polyploid cells show great among-species and among-tissues diversity and relation to
developmental mode, suggesting their importance in adaptive evolution and developmental …

Polyploidy

LE Frawley, TL Orr-Weaver - Current Biology, 2015 - cell.com
Polyploidy is defined as an increase in genome DNA content. Throughout the plant and
animal kingdoms specific cell types become polyploid as part of their differentiation …

Polyploidy in tissue repair and regeneration

EC Bailey, S Kobielski, J Park… - Cold Spring Harbor …, 2021 - cshperspectives.cshlp.org
Polyploidy is defined as a cell with three or more whole genome sets and enables cell
growth across the kingdoms of life. Studies in model organisms have revealed that polyploid …

Physiological significance of polyploidization in mammalian cells

SK Pandit, B Westendorp, A de Bruin - Trends in cell biology, 2013 - cell.com
Programmed polyploidization occurs in all mammalian species during development and
aging in selected tissues, but the biological properties of polyploid cells remain obscure …