Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea‐predominant irritable bowel syndrome

J Zeng, YQ LI, XL ZUO, YB ZHEN… - Alimentary …, 2008 - Wiley Online Library
Background The intestinal permeability is increased in patients with diarrhoea‐predominant
irritable bowel syndrome (D‐IBS). Aim To determine the possible efficacy of lactic acid …

Mucosal permeability and immune activation as potential therapeutic targets of probiotics in irritable bowel syndrome

G Barbara, L Zecchi, R Barbaro… - Journal of clinical …, 2012 - journals.lww.com
There is increasingly convincing evidence supporting the participation of the gut
microenvironment in the pathophysiology of irritable bowel syndrome (IBS). Studies …

The effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind …

BK Cha, SM Jung, CH Choi, ID Song… - Journal of clinical …, 2012 - journals.lww.com
Background: The clinical effect of probiotics on irritable bowel syndrome (IBS) is still
controversial. Aims: We aimed to evaluate the effects of a probiotic mixture on IBS symptoms …

Leaky gut in patients with diarrhea-predominant irritable bowel syndrome and inactive ulcerative colitis

K Gecse, R Róka, T Séra, A Rosztóczy, A Annaházi… - Digestion, 2012 - karger.com
Background/Aims: Defective epithelial barrier has been implicated in the pathogenesis of
irritable bowel syndrome (IBS) and inflammatory bowel diseases. The aim of this study was …

Gut dysbiosis and irritable bowel syndrome: The potential role of probiotics

N Principi, R Cozzali, E Farinelli, A Brusaferro… - Journal of Infection, 2018 - Elsevier
Objective To discuss the role of gut dysbiosis in the development of irritable bowel syndrome
(IBS) and the impact of probiotics as a potential therapeutic measure. Methods PubMed was …

Effect of a preparation of four probiotics on symptoms of patients with irritable bowel syndrome: association with intestinal bacterial overgrowth

K Leventogiannis, P Gkolfakis, G Spithakis… - Probiotics and …, 2019 - Springer
The effect of probiotics on small intestinal bacterial overgrowth (SIBO) in irritable bowel
syndrome (IBS) has never been studied so far. In this prospective trial, five patients with IBS …

The effects of probiotics on symptoms of irritable bowel syndrome

YG Kim, JT Moon, KM Lee, NR Chon… - The Korean journal of …, 2006 - europepmc.org
Methods Forty patients were randomly allocated to be treated with Medilac DS (Bacillus
subtilis, Streptococcus faecium)(n= 20) or placebo (n= 20) in a double-blind, prospective …

Efficacy and Safety of New Lactobacilli Probiotics for Unconstipated Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

JH Oh, YS Jang, D Kang, DK Chang, YW Min - Nutrients, 2019 - mdpi.com
Irritable bowel syndrome (IBS) is a common and chronic gastrointestinal disorder. Probiotics
may have the potential to impact the management of IBS; however, the results of trials are …

Clinical trial: the effects of a trans‐galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome

DBA Silk, A Davis, J Vulevic, G Tzortzis… - Alimentary …, 2009 - Wiley Online Library
Background Gut microflora‐mucosal interactions may be involved in the pathogenesis of
irritable bowel syndrome (IBS). Aim To investigate the efficacy of a novel prebiotic trans …

Probiotics and irritable bowel syndrome: rationale, putative mechanisms, and evidence of clinical efficacy

M Camilleri - Journal of clinical gastroenterology, 2006 - journals.lww.com
The irritable bowel syndrome (IBS) follows an acute, presumably infectious diarrheal illness
in∼ 15% of patients. There may be a persistent, mild inflammatory state with changes in …