Purpose. Chronic myeloid leukemia (CML), a hematopoietic stem cell cancer representing
15–20% of adult leukemias, is discussed. Epidemiology, staging biology, and monitoring …

Reliable epidemiological information on chronic myeloproliferative disorders (CMPDs),
notably Philadelphia (Ph)/BCR-ABL-positive chronic myeloid leukaemia (CML), is rare …

Chronic myelogenous leukemia is a clonal hematopoietic stem disorder characterized by
excess numbers of myeloid cells that over time, lose the capacity for terminal differentiation …

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder that follows a
characteristic clinical course in which a chronic phase of variable duration precedes an …

Chronic myeloid leukaemia (CML) is a clonal myeloproliferative disorder resulting from a
reciprocal translocation between the long arms of chromosomes 9 and 22. This is termed the …

Chronic myeloid leukemia (CML) is a myeloproliferative disorder marked by the increased
proliferation of granulocytic cell lineage cells that retain the ability to differentiate. Nowell …

This chapter summarizes the knowledge regarding the molecular biology of chronic myeloid
leukemia (CML) and the treatment modalities, including novel breakpoint cluster region‐v …

The course of chronic myeloid leukemia (CML) and the response to treatment with tyrosine
kinase inhibitors (TKIs) are best monitored and assessed using two molecular tests: the first …

Elucidation of the pathogenesis of chronic myeloid leukemia (CML) and the introduction of
tyrosine kinase inhibitors (TKIs) has transformed this disease from being invariably fatal to …

Chronic myeloid leukemia provides an illustrative disease model for both molecular
pathogenesis of cancer and rational drug therapy. Chronic myeloid leukemia is a clonal …