Neurodegeneration in multiple sclerosis: relationship to neurological disability
BD Trapp, RM Ransohoff, E Fisher… - The …, 1999 - journals.sagepub.com
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Most MS
patients follow a relapsing-remitting course (RR-MS) for 8 to 15 years that transforms into a …
patients follow a relapsing-remitting course (RR-MS) for 8 to 15 years that transforms into a …
Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis
R Dutta, BD Trapp - Progress in neurobiology, 2011 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system. Due to its high prevalence, MS is the leading cause of non-traumatic …
nervous system. Due to its high prevalence, MS is the leading cause of non-traumatic …
Axonal loss in multiple sclerosis: causes and mechanisms
G Criste, B Trapp, R Dutta - Handbook of clinical neurology, 2014 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system and the leading cause of non-traumatic neurologic disability in young adults …
nervous system and the leading cause of non-traumatic neurologic disability in young adults …
Axonal pathology in multiple sclerosis: relationship to neurologic disability
BD Trapp, R Ransohoff, R Rudick - Current opinion in neurology, 1999 - journals.lww.com
In this review, data is summarized supporting the hypothesis that axonal loss is a major
pathologic process responsible for irreversible neurologic disability in patients with multiple …
pathologic process responsible for irreversible neurologic disability in patients with multiple …
Neurodegeneration in multiple sclerosis involves multiple pathogenic mechanisms
MC Levin, JN Douglas, L Meyers, S Lee… - Degenerative …, 2014 - Taylor & Francis
Multiple sclerosis (MS) is a complex autoimmune disease that impairs the central nervous
system (CNS). The neurological disability and clinical course of the disease is highly …
system (CNS). The neurological disability and clinical course of the disease is highly …
Pathogenesis of tissue injury in MS lesions
BD Trapp, L Bö, S Mörk, A Chang - Journal of neuroimmunology, 1999 - Elsevier
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system. The
primary pathological target in multiple sclerosis is myelin. Most MS patients follow a …
primary pathological target in multiple sclerosis is myelin. Most MS patients follow a …
The pathology of multiple sclerosis
CF Lucchinetti, J Parisi, W Bruck - Neurologic clinics, 2005 - neurologic.theclinics.com
Multiple sclerosis (MS) is a chronic neurologic disease affecting approximately 1 million
adults worldwide and 300,000 Americans [1]. Early illustrations by Carswell in 1838 and …
adults worldwide and 300,000 Americans [1]. Early illustrations by Carswell in 1838 and …
Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences
C Bjartmar, BD Trapp - Current opinion in neurology, 2001 - journals.lww.com
Renewed interest in axonal injury in multiple sclerosis has significantly shifted the focus of
research into this disease toward neurodegeneration. During the past year magnetic …
research into this disease toward neurodegeneration. During the past year magnetic …
Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease
C Bjartmar, JR Wujek, BD Trapp - Journal of the neurological sciences, 2003 - Elsevier
Axonal degeneration has been identified as the major determinant of irreversible
neurological disability in patients with multiple sclerosis (MS). Axonal injury begins at …
neurological disability in patients with multiple sclerosis (MS). Axonal injury begins at …
Axonal degeneration and progressive neurologic disability in multiple sclerosis
C Bjartmar, BD Trapp - Neurotoxicity research, 2003 - Springer
Accumulating data support axonal degeneration as the major determinant of irreversible
neurological disability in patients with multiple sclerosis (MS). The extent of oxonal injury …
neurological disability in patients with multiple sclerosis (MS). The extent of oxonal injury …