Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Most MS
patients follow a relapsing-remitting course (RR-MS) for 8 to 15 years that transforms into a …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system. Due to its high prevalence, MS is the leading cause of non-traumatic …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system and the leading cause of non-traumatic neurologic disability in young adults …

In this review, data is summarized supporting the hypothesis that axonal loss is a major
pathologic process responsible for irreversible neurologic disability in patients with multiple …

Multiple sclerosis (MS) is a complex autoimmune disease that impairs the central nervous
system (CNS). The neurological disability and clinical course of the disease is highly …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system. The
primary pathological target in multiple sclerosis is myelin. Most MS patients follow a …

Multiple sclerosis (MS) is a chronic neurologic disease affecting approximately 1 million
adults worldwide and 300,000 Americans [1]. Early illustrations by Carswell in 1838 and …

Renewed interest in axonal injury in multiple sclerosis has significantly shifted the focus of
research into this disease toward neurodegeneration. During the past year magnetic …

Axonal degeneration has been identified as the major determinant of irreversible
neurological disability in patients with multiple sclerosis (MS). Axonal injury begins at …

Accumulating data support axonal degeneration as the major determinant of irreversible
neurological disability in patients with multiple sclerosis (MS). The extent of oxonal injury …