Toxicity-Induced Discontinuation of Immune Checkpoint Inhibitors in Metastatic Urothelial Cancer: 6-Year Experience from a Specialized Uro-Oncology Center

S Rodler, C Aydogdu, I Brinkmann, E Berg, R Kopliku… - Cancers, 2024 - mdpi.com
Simple Summary This study analyzed patients with metastatic bladder cancer. A total of 108
patients received immunotherapy, but 11 had to stop their immunotherapy because of …

Safety and Efficacy Outcomes in Immune Checkpoint Inhibitor-Treated Patients With Metastatic Urothelial Carcinoma Requiring Treatment Interruption or …

A Nizam, RK Rader, A Tzeng, W Wei, IYF Sheng… - Clinical Genitourinary …, 2024 - Elsevier
Introduction As most patients with metastatic urothelial carcinoma (mUC) will be treated with
immune checkpoint inhibitors (ICI), familiarity with their associated immune-related adverse …

[HTML][HTML] Treatment rechallenge with immune checkpoint inhibitors in advanced urothelial carcinoma

D Makrakis, DR Bakaloudi, R Talukder, GI Lin… - Clinical genitourinary …, 2023 - Elsevier
Objectives: To examine patient and disease characteristics, toxicity, and clinical outcomes
for patients with advanced urothelial carcinoma (aUC) who are rechallenged with immune …

[HTML][HTML] Repeat treatment of patients with advanced urothelial carcinoma with immune checkpoint inhibitors following prior progression on a checkpoint inhibitor …

T Jindal, J Chou, T Friedlander, PC Barata… - Clinical Genitourinary …, 2022 - Elsevier
Abstract Introduction Immune checkpoint inhibitors (ICIs) have become one of the mainstays
of systemic therapy for advanced urothelial carcinoma (aUC). Increasingly ICIs are also …

Five-Year Outcome and Safety in Patients Treated With Immune Checkpoint Blockade Therapies for Urothelial Carcinoma: Experience From Real-World Clinical …

D Tural, C Arslan, F Selcukbiricik, OF Olmez… - Clinical Genitourinary …, 2023 - Elsevier
Background In this study, we report real-world results from the 5-year follow-up data of
urothelial carcinoma patients treated with immune checkpoint blockade therapies (ICTs) …

Single-centre experience of patients with metastatic urothelial cancer treated with chemotherapy following immune checkpoint inhibition

JM Lam, WK Liu, T Powles, YZ Tang… - European Urology …, 2021 - Elsevier
There are few data on outcomes for patients with metastatic urothelial carcinoma (MUC) who
receive chemotherapy (CT) after progression on immune checkpoint inhibitors (ICIs). We …

Clinical outcomes of patients with metastatic urothelial carcinoma after progression to immune checkpoint inhibitors: a retrospective analysis by the Meet-Uro Group …

M Bersanelli, S Buti, A Cortellini… - Clinical Medicine …, 2021 - journals.sagepub.com
Background: Immune checkpoint inhibitors (ICIs) are currently the standard of care for
metastatic urothelial cancer (mUC) after the failure of previous platinum-based …

Response rate to chemotherapy after immune checkpoint inhibition in metastatic urothelial cancer

B Szabados, N van Dijk, YZ Tang, MS van der Heijden… - European urology, 2018 - Elsevier
Immune checkpoint inhibitors (ICIs) are active in metastatic urothelial carcinoma (MUC).
They have joined chemotherapy (CT) as a standard of care. Here, we investigate the activity …

Safety and efficacy of immune checkpoint inhibitors for patients with metastatic urothelial carcinoma and end-stage renal disease: experiences from real-world practice

MC Kuo, PJ Su, CC Huang, HL Luo, TJ Chiu… - Frontiers in …, 2020 - frontiersin.org
Background Immune checkpoint inhibitors (ICIs) are used widely for treating metastatic
urothelial carcinoma (mUC). In practical settings, evidence is lacking on the efficacy of ICIs …

Immune-related adverse events and clinical outcomes in advanced urothelial cancer patients treated with immune checkpoint inhibitors

GE Sanda, JM Shabto, S Goyal, Y Liu, DJ Martini… - The …, 2023 - academic.oup.com
Background In advanced urothelial cancers (UC), immune checkpoint inhibitors (ICI) show
promise as a durable therapy. Immune-related adverse events (irAEs), a side effect of ICIs …