Background Endoplasmic reticulum (ER) stress is involved in many neurological and
inflammatory responses. Peripheral inflammatory responses can induce central sensitization …

Background: Ethyl pyruvate (EP) possesses anti-inflammatory activity. However, the
potential anti-nociceptive value of EP for the treatment of the inflammatory nociception is …

Endoplasmic reticulum (ER) stress is involved in many neurological diseases and
inflammatory responses. Inflammatory mediators induce neuronal damage and trigger the …

In the present study, we investigated the role of phosphorylated calcium/calmodulin-
dependent protein kinase II (pCaMK-II) and phosphorylated extracellular signal-regulated …

The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER)
lumen leads to ER stress, which is related to cellular reactive oxygen species production …

Abstract Editor's Perspective What We Already Know about This Topic The mechanisms
supporting bone cancer pain are incompletely understood Stress of the endoplasmic …

The formalin test produces 2 well-known acute phases of nociceptive behavior. Recently, we
have shown that this same formalin test produces a third phase of nociceptive behavior …

This study compares the effects of two non-steroidal anti-inflammatory drugs, Bufferin A (BA)
and L-5409709 (L-54), on nociceptive behaviour and spinal Fos expression induced by …

Pain is a complex and multifaceted experience. Recent research has increasingly focused
on the role of endoplasmic reticulum (ER) stress in the induction and modulation of pain …

Currently, the clinical management of visceral pain remains unsatisfactory for many patients
suffering from this disease. While preliminary animal studies have suggested the …