[HTML][HTML] An integrative data mining and omics-based translational model for the identification and validation of oncogenic biomarkers of pancreatic cancer

NP Long, KH Jung, NH Anh, HH Yan, TD Nghi, S Park… - Cancers, 2019 - mdpi.com
Substantial alterations at the multi-omics level of pancreatic cancer (PC) impede the
possibility to diagnose and treat patients in early stages. Herein, we conducted an …

[HTML][HTML] Integrative analysis of multi-omics data for identifying multi-markers for diagnosing pancreatic cancer

MS Kwon, Y Kim, S Lee, J Namkung, T Yun, SG Yi… - BMC genomics, 2015 - Springer
Background microRNA (miRNA) expression plays an influential role in cancer classification
and malignancy, and miRNAs are feasible as alternative diagnostic markers for pancreatic …

[HTML][HTML] Integrated transcriptomic analysis reveals hub genes involved in diagnosis and prognosis of pancreatic cancer

YY Zhou, LP Chen, Y Zhang, SK Hu, ZJ Dong, M Wu… - Molecular …, 2019 - Springer
Background The hunt for the molecular markers with specificity and sensitivity has been a
hot area for the tumor treatment. Due to the poor diagnosis and prognosis of pancreatic …

[HTML][HTML] Prediction of survival and recurrence in patients with pancreatic cancer by integrating multi-omics data

B Baek, H Lee - Scientific reports, 2020 - nature.com
Predicting the prognosis of pancreatic cancer is important because of the very low survival
rates of patients with this particular cancer. Although several studies have used microRNA …

Robust identification of common genomic biomarkers from multiple gene expression profiles for the prognosis, diagnosis, and therapies of pancreatic cancer

MB Hossen, MA Islam, MS Reza, MK Kibria… - Computers in Biology …, 2023 - Elsevier
Pancreatic cancer (PC) is one of the leading causes of cancer-related death globally. So,
identification of potential molecular signatures is required for diagnosis, prognosis, and …

[HTML][HTML] Current state of “omics” biomarkers in pancreatic cancer

B Turanli, E Yildirim, G Gulfidan, KY Arga… - Journal of Personalized …, 2021 - mdpi.com
Pancreatic cancer is one of the most fatal malignancies and the seventh leading cause of
cancer-related deaths related to late diagnosis, poor survival rates, and high incidence of …

[HTML][HTML] Identification of key regulators of pancreatic cancer progression through multidimensional systems-level analysis

D Rajamani, MK Bhasin - Genome Medicine, 2016 - Springer
Background Pancreatic cancer is an aggressive cancer with dismal prognosis, urgently
necessitating better biomarkers to improve therapeutic options and early diagnosis …

[HTML][HTML] RUNX2 and LAMC2: promising pancreatic cancer biomarkers identified by an integrative data mining of pancreatic adenocarcinoma tissues

G Jin, Q Ruan, F Shangguan, L Lan - Aging (albany NY), 2021 - ncbi.nlm.nih.gov
Pancreatic carcinoma (PC) is a severe disease associated with high mortality. Although
strategies for cancer therapy have made great progress, outcomes of pancreatic carcinoma …

[HTML][HTML] Multi-omics analyses based on genes associated with oxidative stress and phospholipid metabolism revealed the intrinsic molecular characteristics of …

H Wang, H Guo, J Sun, Y Wang - Scientific Reports, 2023 - nature.com
Oxidative stress (OS), which impacts lipid metabolic reprogramming, can affect the biological
activities of cancer cells. How oxidative stress and phospholipid metabolism (OSPM) …

[HTML][HTML] Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics …

J Ding, Y Liu, Y Lai - PeerJ, 2020 - peerj.com
Background Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant neoplasm. It is
necessary to improve the understanding of the underlying molecular mechanisms and …