Necroptosis is a caspase-independent form of programmed cell death executed by the
receptor interacting protein kinase 1 (RIPK1)-RIPK3-mixed lineage kinase domain-like …

Necroptosis, or regulated necrosis, is an important type of programmed cell death in addition
to apoptosis. Necroptosis induction leads to cell membrane disruption, inflammation and …

Necroptosis, known as programmed necrosis, is a form of caspase-independent, finely
regulated cell death with necrotic morphology. Tumor necrosis, foci of necrotic cell death …

Under stress conditions, cells in living tissue die by apoptosis or necrosis depending on the
activation of the key molecules within a dying cell that either transduce cell survival or death …

In the past few decades, apoptosis has been regarded as the only form of programmed cell
death. However, the traditional view has been challenged by the identification of several …

Necroptosis is a tightly regulated form of necrosis that requires the activation of receptor-
interacting protein (RIP) kinases RIPK1 and RIPK3, as well as the RIPK3 substrate mixed …

A newly discovered mechanism of cell death, programmed necrosis (necroptosis), combines
features of both necrosis and apoptosis. Necroptosis is tightly modulated by a series of …

Necroptosis is a form of programmed necrosis whose molecular players are partially shared
with apoptotic cell death. Here we summarize what is known about molecular signalling of …

Necroptosis, a form of regulated necrotic cell death, is mediated by receptor interacting
protein 1 (RIPK1), RIPK3, and mixed lineage kinase domain-like protein (MLKL). However …

Necrosis is a hallmark of several widespread diseases or their direct complications. In the
past decade, we learned that necrosis can be a regulated process that is potentially …