Introduction Cytisinicline (known as cytisine), a nicotinic acetylcholine receptor partial
agonist, is a smoking cessation aid currently marketed in Central and Eastern Europe using …

A number of new N-substituted cytisine derivatives were prepared and tested, along with
similar compounds already described by us and others, as high affinity neuronal …

The availability of drug affecting neuronal nicotinic acetylcholine receptors (nAChRs) may
have important therapeutic potential for the treatment of several CNS pathologies. Pursuing …

ETHNOPHARMACOLOGICAL RELEVANCE: Plants of the family Amaryllidaceae are used
widely in traditional medicine in South Africa. Several of these, including representatives of …

Abstract Objectives Cinnamomi ramulus (called Guizhi in Chinese) is a traditional medicine
used to treat gastrointestinal dysfunction, cancer, arthritis, osteoporosis, spleen deficiency …

Multiple chromatographic separations of the CHCl3-soluble extract of the roots of Echinacea
purpurea led to the isolation of 19 compounds. Four natural products, three alkamides and …

Varenicline, a new nicotinic ligand based on the structure of cytisine, has recently been
approved by the US Food and Drug Administration for use as a smoking cessation aid …

Nicotinic acetylcholine receptor agonists are considered potential pharmacological agents
for Parkinson's Disease treatment, due to their ability to improve experimental Parkinson …

Ethnopharmacological relevance Aconitine, a C 19-norditerpenoid alkaloid, derives from
many medicinal plants such as Aconitum carmichaelii Debx.(Chinese: 乌头), Aconitum …

Microcos paniculata is a large shrub or small tree that grows in several countries in South
and Southeast Asia. In the present study, three new piperidine alkaloids, microgrewiapines …